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Protein

Glucose-6-phosphate isomerase 2

Gene

pgi2

Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase 1 (pgi1), Glucose-6-phosphate isomerase 2 (pgi2)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei357Proton donorUniRule annotation1
Active sitei388UniRule annotation1
Active sitei514UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCVIO243365:G1G08-2368-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 2UniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPI 2UniRule annotation
Alternative name(s):
Phosphoglucose isomerase 2UniRule annotation
Short name:
PGI 2UniRule annotation
Phosphohexose isomerase 2UniRule annotation
Short name:
PHI 2UniRule annotation
Gene namesi
Name:pgi2UniRule annotation
Ordered Locus Names:CV_2369
OrganismiChromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Taxonomic identifieri243365 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeChromobacterium
Proteomesi
  • UP000001424 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806251 – 550Glucose-6-phosphate isomerase 2Add BLAST550

Interactioni

Protein-protein interaction databases

STRINGi243365.CV_2369

Structurei

3D structure databases

ProteinModelPortaliQ7NVH4
SMRiQ7NVH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiQAETHAM
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q7NVH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQRHIDIN STQVWAKLHQ HQRATRHMHM RELFELDPQR FQRFSLELDG
60 70 80 90 100
LLLDYSKNRV TERTLELLFD LARKADLRGW MDRMRSGERI NVSENRSVLH
110 120 130 140 150
TALRLPAGAR LDLEGHNVAA DVHQVLARLK DFSEQVREGR WLGFAGQPIR
160 170 180 190 200
DVVNLGIGGS DLGPLVAADA LAAYAHPDLK VHFVSNVDGQ HLARTLERLN
210 220 230 240 250
PATTLFIVAS KSFTTPETLL NAQAARAWFL QAAGEAQIAK HFVAVSTNEP
260 270 280 290 300
AVRAFGIDPQ HMFGFWDWVG GRYSVWSAIG LPVMLSIGYD NFRAFLDGGH
310 320 330 340 350
AMDRHFFESP FDANMPVLLA LIGIWYNTFY RAHTHAIMPY DHGLRRLPAH
360 370 380 390 400
IQQLDMESNG KRVGRLGEAL DFDTGPVIWG EEGANSQHAF FQLLHQGTRL
410 420 430 440 450
VPCDFILPLN SHYPLGNQHD VLVANCLAQT EALMRGKNEA EVMRELSHLS
460 470 480 490 500
GEQLDMLLPQ KLFPGNQPSN TLALDRVTPY SMGMLMALYE HKVFVQGVIW
510 520 530 540 550
GINSFDQWGV EYGKQLARRI LPELSGDTGA LGHDSSTNGL IRHYRERHGK
Length:550
Mass (Da):61,928
Last modified:December 15, 2003 - v1
Checksum:iEF08BD1CE44301AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016825 Genomic DNA Translation: AAQ60041.1
RefSeqiWP_011135916.1, NC_005085.1

Genome annotation databases

EnsemblBacteriaiAAQ60041; AAQ60041; CV_2369
GeneIDi24948028
KEGGicvi:CV_2369

Similar proteinsi

Entry informationi

Entry nameiG6PI2_CHRVO
AccessioniPrimary (citable) accession number: Q7NVH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: December 15, 2003
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome