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Reviewed, UniProtKB/Swiss-Prot Q7NSK2 (PNCB_CHRVO)

Last modified February 9, 2010. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11
Gene names
Name: pncB
Ordered Locus Names: CV_3422
OrganismChromobacterium violaceum [Complete proteome] [HAMAP]
Taxonomic identifier536 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeChromobacterium

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570

Subcellular location

Cytoplasm By similarity HAMAP MF_00570.

Sequence similarities

Belongs to the NAPRTase family.

Ontologies

Keywords
   Biological processPyridine nucleotide biosynthesis
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processNAD biosynthetic process

Inferred from electronic annotation. Source: HAMAP

nicotinate nucleotide biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnicotinate phosphoribosyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Nicotinate phosphoribosyltransferase HAMAP MF_00570
PRO_0000205827

Sequences

Sequence LengthMass (Da)Tools
Q7NSK2-1 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 99494737859FE6E0

FASTA40246,340
        10         20         30         40         50         60 
MPKNTPIIRS LLDTDLYKFT MLQVVLHQFP AAHGEYEFRC RNHPDTPLTQ LKQQLETQLD 

        70         80         90        100        110        120 
LLCELRFSQD ELDYLRGLRF IKSDYVDYLE LFHLQRRFIS VSEEGEQLAI RIKGPMVQAM 

       130        140        150        160        170        180 
FFEIFVLAIV NELYFRPLDS KAVREEGRRR LEAKLAELER FQREEAPGQR FPLLIADFGT 

       190        200        210        220        230        240 
RRRFSRDWQA HVVERLNHAL PQVFRGTSNV YLARKLGITP IGTMAHEFFQ AFQALGVRLR 

       250        260        270        280        290        300 
DFQKAALESW VQEYRGDLGI ALTDVVGMDA FLADFDLYFA KLFDGLRHDS GDPYIWGEKA 

       310        320        330        340        350        360 
IAHYRKLRID PATKMLTFSD GLSVDSALQL QRHFSPHIQV SFGIGTHFTN DMGLEPLQIV 

       370        380        390        400 
LKLVSCNGQP VAKLSDSPGK TMCSDETFLA YLRQVFKVPA LA 

« Hide

References

[1]"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability."
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A. expand/collapse author list , van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003) [PubMed: 14500782] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016825 Genomic DNA. Translation: AAQ61085.1.
RefSeqNP_903092.1.

3D structure databases

SMRQ7NSK2. Positions 2-398.
ModBaseSearch...

Genome annotation databases

GeneID2548424.
GenomeReviewsGene locus CV_3422 in contig AE016825_GR.
KEGGcvi:CV_3422.
NMPDRfig|243365.1.peg.3422.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG325503.
OMALYKFTML.
PhylomeDBQ7NSK2.

Enzyme and pathway databases

BioCycCVIO243365:CV_3422-MONOMER.
BRENDA2.4.2.11. 415.

Family and domain databases

HAMAPMF_00570. NAPRTase.
[Tree]
InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
[Graphical view]
PANTHERPTHR11098:SF1. NAPRTase. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_CHRVO
AccessionPrimary (citable) accession number: Q7NSK2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 15, 2003
Last modified: February 9, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents