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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciCVIO243365:G1G08-3447-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:CV_3431
OrganismiChromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Taxonomic identifieri243365 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeChromobacterium
Proteomesi
  • UP000001424 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225521 – 362AminomethyltransferaseAdd BLAST362

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi243365.CV_3431

Structurei

3D structure databases

ProteinModelPortaliQ7NSJ3
SMRiQ7NSJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239380
KOiK00605
OMAiMPVQYPA
OrthoDBiPOG091H04FV

Family and domain databases

Gene3Di3.30.1360.1202 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

Q7NSJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPKRTPLF DAHIAAGAKM VDFAGWEMPI HYGSQLKEHE IVRSDAGMFD
60 70 80 90 100
VSHMTVIDIT GADAKAWLQK LIANDVAKLG FEGKALYSGM LTPEGTVVDD
110 120 130 140 150
LIVYLTAYGY RMVVNAGTTE KDLAWMESQK AGFDVALKVR RDLAMLAVQG
160 170 180 190 200
PKAIQKVCSI KPELAEAIRA LKVFQGLPQG EWFYARTGYT GEDGLEIMVP
210 220 230 240 250
ADQAISFFHQ LQAAGVSPIG LGARDTLRLE AGMNLYGHDM DETVSPLEAG
260 270 280 290 300
MGWTIAWEPA ERKFNGREAL EAQKAAGVKM KQVGLVLEGR GVLREGLKVV
310 320 330 340 350
VESVGEGVIT SGTFSPTLKH SIAIARVPAA TGAAAQVDLR GTLTDVRVVK
360
MPFVRNGKKV FE
Length:362
Mass (Da):39,135
Last modified:December 15, 2003 - v1
Checksum:i8FBF823ADFFEC12A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016825 Genomic DNA Translation: AAQ61094.1
RefSeqiWP_011136978.1, NC_005085.1

Genome annotation databases

EnsemblBacteriaiAAQ61094; AAQ61094; CV_3431
GeneIDi24947789
KEGGicvi:CV_3431

Similar proteinsi

Entry informationi

Entry nameiGCST_CHRVO
AccessioniPrimary (citable) accession number: Q7NSJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: December 15, 2003
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome