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Q7NMP5

- PUR5_GLOVI

UniProt

Q7NMP5 - PUR5_GLOVI

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Gloeobacter violaceus (strain PCC 7421)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGVIO251221:GH9A-727-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:gll0720
OrganismiGloeobacter violaceus (strain PCC 7421)
Taxonomic identifieri251221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter
ProteomesiUP000000557: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 337337Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148214Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi251221.gvip076.

Structurei

3D structure databases

ProteinModelPortaliQ7NMP5.
SMRiQ7NMP5. Positions 1-333.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
InParanoidiQ7NMP5.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.
PhylomeDBiQ7NMP5.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7NMP5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDYKSAGVDV EAGYEFVARI RGAVERTRRP EQLGGLGGFG GLFALPAGYR
60 70 80 90 100
EPVLVAGTDG VGTKLKLAFA LDRHDTIGID CVAMCVNDVL AQGAEPLFFL
110 120 130 140 150
DYLATGKLSP AQLAGVVEGI AAGCLEAGCT LLGGETAEMP GFYAAGEYDV
160 170 180 190 200
AGFCVGIVER SQIIDGNRVQ VGDALLGLSS SGVHSNGFSL VRRIVELAGL
210 220 230 240 250
DWHHRPEDFP ASLGEVLLTP TRIYVKPVRA ALEAGFDIRG IAHITGGGLI
260 270 280 290 300
ENVPRALGGL GACLERNSWP VPPVFTWLER TGGVGRQDMD QTFNLGLGLV
310 320 330
LACPTEQADA LQAYLAKQGE QVLRIGAVVE AAGVRFA
Length:337
Mass (Da):35,366
Last modified:December 15, 2003 - v1
Checksum:i35EF194D0C4E0B26
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000045 Genomic DNA. Translation: BAC88661.1.
RefSeqiNP_923666.1. NC_005125.1.

Genome annotation databases

EnsemblBacteriaiBAC88661; BAC88661; BAC88661.
GeneIDi2599439.
KEGGigvi:gvip076.
PATRICi22040823. VBIGloVio86258_0733.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000045 Genomic DNA. Translation: BAC88661.1 .
RefSeqi NP_923666.1. NC_005125.1.

3D structure databases

ProteinModelPortali Q7NMP5.
SMRi Q7NMP5. Positions 1-333.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 251221.gvip076.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC88661 ; BAC88661 ; BAC88661 .
GeneIDi 2599439.
KEGGi gvi:gvip076.
PATRICi 22040823. VBIGloVio86258_0733.

Phylogenomic databases

eggNOGi COG0150.
InParanoidi Q7NMP5.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.
PhylomeDBi Q7NMP5.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci GVIO251221:GH9A-727-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7421.

Entry informationi

Entry nameiPUR5_GLOVI
AccessioniPrimary (citable) accession number: Q7NMP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: December 15, 2003
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3