ID   Q7NM54_GLOVI            Unreviewed;       483 AA.
AC   Q7NM54;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   27-MAR-2024, entry version 121.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=glr0915 {ECO:0000313|EMBL:BAC88856.1};
OS   Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gloeobacterales; Gloeobacteraceae;
OC   Gloeobacter.
OX   NCBI_TaxID=251221 {ECO:0000313|EMBL:BAC88856.1, ECO:0000313|Proteomes:UP000000557};
RN   [1] {ECO:0000313|EMBL:BAC88856.1, ECO:0000313|Proteomes:UP000000557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421 {ECO:0000313|Proteomes:UP000000557};
RX   PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids.";
RL   DNA Res. 10:137-145(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; BA000045; BAC88856.1; -; Genomic_DNA.
DR   RefSeq; NP_923861.1; NC_005125.1.
DR   RefSeq; WP_011140917.1; NC_005125.1.
DR   AlphaFoldDB; Q7NM54; -.
DR   STRING; 251221.gene:10758393; -.
DR   EnsemblBacteria; BAC88856; BAC88856; BAC88856.
DR   KEGG; gvi:glr0915; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG5616; Bacteria.
DR   HOGENOM; CLU_564706_0_0_3; -.
DR   InParanoid; Q7NM54; -.
DR   OrthoDB; 9788659at2; -.
DR   PhylomeDB; Q7NM54; -.
DR   Proteomes; UP000000557; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:BAC88856.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000000557};
KW   Transferase {ECO:0000313|EMBL:BAC88856.1}.
FT   DOMAIN          34..284
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   BINDING         65
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   483 AA;  52390 MW;  F8042E2EE60A8CE4 CRC64;
     MAVEPPPQHD EYRCAAAQPM GEEPLSAGQR LGAYRIIRPV GQGGMGAVYL AERDDGQFDK
     RAAVKILQPQ LHGPGLRERF IGERQILASL DHPYITRLLD GGTTEQGLPY LVMDYVEGQP
     INLYCNERKL DVDERLRLFL KVCEAVHYAH AHRVIHRDLK PANILIDPEG NPRLLDFGIA
     KLLPADPEAT AVFSQSMTRL LTPGYASPEQ IKGEAITPAS DEYSLAVVLC ELLSGRRPGE
     ATPQQLTGKL AGPLASLVLK ALCEDPLDRF GSVAAFSLAI ERHLTGQALP WPRTGTLLWP
     IRAHRRLVTA MAAACLAVGL GWWSLQAAVP PARRAIAVLP FENLSGDGRS AYFSKGVAVD
     LADQLGKTGR FTIIAGRAAT GGSHHHLRRP FGTEAVLSGS VRRTGGHIRV VSQLIDARSG
     VQLWSESFDR PLQSGFADQT EVARQIVGAL ESQYSPVRKT IAPKSRSAKA NCLQNFCPSG
     GPN
//