Q7NLT3 (AROA_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	gll1038

Organism

Gloeobacter violaceus (strain PCC 7421)

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000012436

Sequences

	Sequence		Length	Mass (Da)
	Q7NLT3 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 62ACB6D316E0A5B3	FASTA	432	45,310
	10 20 30 40 50 60 MGQAFSITPA RRLSGEIAVA GDKSISHRAL MLAALAEGES VIEGLLPGDD PRSTAACLRA 70 80 90 100 110 120 LGAEISGIDG PSVRVRGVGL GRLHEPADVL DMGNSGTTMR LMLGVLAGQP GLFCTLTGDR 130 140 150 160 170 180 SLRSRPMLRV VSPLRQMGAR IWGREEGGRA PLAVWGEQLR AIDFVSPVAS AQVKSAVLLA 190 200 210 220 230 240 GLLAEGLTSV SEPVRSRDHS ERMLRAFGAE VLVDGTTAAV RGPARLRAQS LRVPGDISSA 250 260 270 280 290 300 AFWLVAGSIV PDSQLLLSGV GVNPTRTGVL DALAAMGADI AVENRREVCG EPVADLRVRS 310 320 330 340 350 360 APLKACTIGG EWIPRLVDEI PVLAVAACCA AGKTVIRDAA ELRVKESDRL ATMARELGRL 370 380 390 400 410 420 GAHIEERPDG LVIEGGHRLV GAGVESHDDH RVAMSLAVAG LVATGTTEIA DPDCATVSYP 430 QFYEHLARVR QQ

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC88979.1.
RefSeq	NP_923984.1. NC_005125.1.
3D structure databases
HSSP	HSSP built from PDB template 1RF6 based on UniProtKB Q9S400.
ProteinModelPortal	Q7NLT3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2599156.
GenomeReviews	Gene locus gll1038 in contig BA000045_GR.
NMPDR	fig|251221.1.peg.1038.
PATRIC	22041487. VBIGloVio86258_1063.
Phylogenomic databases
HOGENOM	HBG646626.
OMA	LECANIS.
PhylomeDB	Q7NLT3.
ProtClustDB	PRK02427.
Enzyme and pathway databases
BioCyc	GVIO251221:GLL1038-MONOMER.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_GLOVI

Accession

Primary (citable) accession number: Q7NLT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program