Q7NK35 (PHS2_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase 2
Short name=PHS 2
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase 2
Pterin carbinolamine dehydratase 2
Short name=PCD 2

Gene names

Ordered Locus Names:

gsl1645

Organism

Gloeobacter violaceus (strain PCC 7421)

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Putative pterin-4-alpha-carbinolamine dehydratase 2 HAMAP MF_00434		PRO_0000063082

Sequences

	Sequence		Length	Mass (Da)
	Q7NK35 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 12E802C8BE749248	FASTA	92	10,201
	10 20 30 40 50 60 MNKMTPEEIE TALKPIADWQ LSEADGATAI ERVFRFDDFV QAIAFVNKVA ERAETAGHHP 70 80 90 DIHIHYNRVR LVLSTHDAGG VTSKDLEMAA AL

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC89586.1.
RefSeq	NP_924591.1. NC_005125.1.
3D structure databases
ProteinModelPortal	Q7NK35.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2598518.
GenomeReviews	Gene locus gsl1645 in contig BA000045_GR.
KEGG	gvi:gsl1645.
NMPDR	fig|251221.1.peg.1645.
PATRIC	22042745. VBIGloVio86258_1680.
Phylogenomic databases
HOGENOM	HBG705804.
OMA	IALICEK.
PhylomeDB	Q7NK35.
Enzyme and pathway databases
BioCyc	GVIO251221:GSL1645-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS2_GLOVI

Accession

Primary (citable) accession number: Q7NK35

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program