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Q7NJY9 (G6PI_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:gll1692
OrganismGloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP]
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 548548Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180648

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7NJY9 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 6C469090ACEF3C03

FASTA54861,509
        10         20         30         40         50         60 
MTSTFAPTPL TQRAAWQALA AHYEQIREIH LRALFAEDPS RGERFALEAE GFYLDYSKNR 

        70         80         90        100        110        120 
LTDETLRLLS VLAEESDLRG RIEAMFSGEK INTTEQRSVL HTALRAPRGA TVIEDGENVV 

       130        140        150        160        170        180 
PEVHAVLDRM AEFADRVRGG EWRGYTGRRI RTVVNIGIGG SYLGPDMAYD ALKHYSDRDL 

       190        200        210        220        230        240 
KVRFAANVDG SNFAEVIHDL EPDETLFIVC SKTFTTLETM TNAHSARQWC LAALGDEQAI 

       250        260        270        280        290        300 
AKHFVAVSTN AAEVEKFGID TAHMFGFWDW VGGRYSMDSA IGLSTMIAVG PEHFRAMLAG 

       310        320        330        340        350        360 
FHAMDEHFRT APFERNLPVL MALIGLWYNN FFGAQTLAVL PYDYYLGKLP AYLQQLDMES 

       370        380        390        400        410        420 
NGKHVDIDGQ PVTYQTGPII WGQPGTDGQH SFYQLIHQGT KLIPCDFIGF CQTLNPIAPH 

       430        440        450        460        470        480 
HDQLMANFFA QTEALAFGKT EAEVRAEGVA DWLLPHRVFE GNRPTNTLLA ERLTPEVLGK 

       490        500        510        520        530        540 
LIALYEHKVF TQGVIWNLDS FDQWGVELGK VLAGRIIPEL ESAEEPELAH DSSTNALIRR 


YRRAKRQN 

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References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000045 Genomic DNA. Translation: BAC89633.1.
RefSeqNP_924638.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NJY9.
SMRQ7NJY9. Positions 6-545.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING251221.gll1692.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC89633; BAC89633; BAC89633.
GeneID2598472.
KEGGgvi:gll1692.
PATRIC22042837. VBIGloVio86258_1725.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.
PhylomeDBQ7NJY9.

Enzyme and pathway databases

BioCycGVIO251221:GH9A-1714-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_GLOVI
AccessionPrimary (citable) accession number: Q7NJY9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: December 15, 2003
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways