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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Gloeobacter violaceus (strain PCC 7421)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei359 – 3591Proton donorUniRule annotation
Active sitei390 – 3901UniRule annotation
Active sitei510 – 5101UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciGVIO251221:GH9A-1714-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:gll1692
OrganismiGloeobacter violaceus (strain PCC 7421)
Taxonomic identifieri251221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter
ProteomesiUP000000557 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomerasePRO_0000180648Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi251221.gll1692.

Structurei

3D structure databases

ProteinModelPortaliQ7NJY9.
SMRiQ7NJY9. Positions 6-545.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
InParanoidiQ7NJY9.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.
PhylomeDBiQ7NJY9.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7NJY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSTFAPTPL TQRAAWQALA AHYEQIREIH LRALFAEDPS RGERFALEAE
60 70 80 90 100
GFYLDYSKNR LTDETLRLLS VLAEESDLRG RIEAMFSGEK INTTEQRSVL
110 120 130 140 150
HTALRAPRGA TVIEDGENVV PEVHAVLDRM AEFADRVRGG EWRGYTGRRI
160 170 180 190 200
RTVVNIGIGG SYLGPDMAYD ALKHYSDRDL KVRFAANVDG SNFAEVIHDL
210 220 230 240 250
EPDETLFIVC SKTFTTLETM TNAHSARQWC LAALGDEQAI AKHFVAVSTN
260 270 280 290 300
AAEVEKFGID TAHMFGFWDW VGGRYSMDSA IGLSTMIAVG PEHFRAMLAG
310 320 330 340 350
FHAMDEHFRT APFERNLPVL MALIGLWYNN FFGAQTLAVL PYDYYLGKLP
360 370 380 390 400
AYLQQLDMES NGKHVDIDGQ PVTYQTGPII WGQPGTDGQH SFYQLIHQGT
410 420 430 440 450
KLIPCDFIGF CQTLNPIAPH HDQLMANFFA QTEALAFGKT EAEVRAEGVA
460 470 480 490 500
DWLLPHRVFE GNRPTNTLLA ERLTPEVLGK LIALYEHKVF TQGVIWNLDS
510 520 530 540
FDQWGVELGK VLAGRIIPEL ESAEEPELAH DSSTNALIRR YRRAKRQN
Length:548
Mass (Da):61,509
Last modified:December 15, 2003 - v1
Checksum:i6C469090ACEF3C03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000045 Genomic DNA. Translation: BAC89633.1.
RefSeqiNP_924638.1. NC_005125.1.

Genome annotation databases

EnsemblBacteriaiBAC89633; BAC89633; BAC89633.
GeneIDi2598472.
KEGGigvi:gll1692.
PATRICi22042837. VBIGloVio86258_1725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000045 Genomic DNA. Translation: BAC89633.1.
RefSeqiNP_924638.1. NC_005125.1.

3D structure databases

ProteinModelPortaliQ7NJY9.
SMRiQ7NJY9. Positions 6-545.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi251221.gll1692.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC89633; BAC89633; BAC89633.
GeneIDi2598472.
KEGGigvi:gll1692.
PATRICi22042837. VBIGloVio86258_1725.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
InParanoidiQ7NJY9.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.
PhylomeDBiQ7NJY9.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciGVIO251221:GH9A-1714-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7421.

Entry informationi

Entry nameiG6PI_GLOVI
AccessioniPrimary (citable) accession number: Q7NJY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: December 15, 2003
Last modified: April 29, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.