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Q7NJG5 (Q7NJG5_GLOVI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:glr1867
OrganismGloeobacter violaceus (strain PCC 7421)
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q7NJG5 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 6459952CFE803D95

FASTA28530,594
        10         20         30         40         50         60 
MNPPALTTPL IHPSAVIHPR AVLHESVQVG PFAVVGEHVR IGAGTVVGPH AVIDGWTEIG 

        70         80         90        100        110        120 
CDNVIYNGAS IGTPPQDLKY RNEPSRVRIG DNNDIREFVT VNRGTDKGSE TVVGDKNLLM 

       130        140        150        160        170        180 
AYVHVGHNCA IGDNVVITNA VMLAGHVHIE SQARIGGLVG VHQFVHIGRL AYIGGMARVD 

       190        200        210        220        230        240 
RDVPPFTLVE GHPGRTRGLN WVGLERAGIS DAAGADRESY RLLRQAYKLL YRSATPLEKA 

       250        260        270        280 
LVELQALAGN PYIDHLHTFL SRSVGDPARR GPTPAARKRP GGDDA

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References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000045 Genomic DNA. Translation: BAC89808.1.
RefSeqNP_924813.1. NC_005125.1.

3D structure databases

HSSPHSSP built from PDB template 1J2Z based on UniProtKB O25927.
ProteinModelPortalQ7NJG5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2600269.
GenomeReviewsGene locus glr1867 in contig BA000045_GR.
KEGGgvi:glr1867.
NMPDRfig|251221.1.peg.1867.
PATRIC22043189. VBIGloVio86258_1900.

Phylogenomic databases

HOGENOMHBG659295.
OMAGDKNLLM.
PhylomeDBQ7NJG5.
ProtClustDBPRK05289.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7NJG5_GLOVI
AccessionPrimary (citable) accession number: Q7NJG5
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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