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Q7NHM2 (AROB_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:glr2513
OrganismGloeobacter violaceus (strain PCC 7421)
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3613613-dehydroquinate synthase HAMAP MF_00110
PRO_0000140741

Sequences

Sequence LengthMass (Da)Tools
Q7NHM2 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: AE2736E2E75000C3

FASTA36139,371
        10         20         30         40         50         60 
MIRIPVALPM DSYDICIDEG GLERLGEYLA ELGKVNRALV VSNPVVLRHY GARVVRSLNA 

        70         80         90        100        110        120 
AGFETASVTV PAGERHKHLR SVERIYQAAL EHRLERSSLI VALGGGVVGD MAGFAASTWL 

       130        140        150        160        170        180 
RGIRVAQVPT TLLAMVDAAI GGKTGVNHPL GKNLIGTFHQ PCLVLIDPQV LGTLPPRETR 

       190        200        210        220        230        240 
AAMAEVIKYG VIWDGDLFKR LEQLPSLQRP DARTLTTLLV RSCQAKAEVV VRDEREGGLR 

       250        260        270        280        290        300 
AILNYGHTVG HALESATGYR RYLHGEGVAL GMAAAGRVAV ALDLWSPEEL RRQEALIIKA 

       310        320        330        340        350        360 
RLPVRWKSDI ASEALLLRMQ SDKKVEAGKV RFVLPEAIGR VHTGVEVPTE VLRRVLDTLR 


G

« Hide

References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000045 Genomic DNA. Translation: BAC90454.1.
RefSeqNP_925459.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NHM2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2600914.
GenomeReviewsGene locus glr2513 in contig BA000045_GR.
NMPDRfig|251221.1.peg.2513.
PATRIC22044505. VBIGloVio86258_2551.

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ7NHM2.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycGVIO251221:GLR2513-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_GLOVI
AccessionPrimary (citable) accession number: Q7NHM2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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