Q7NHL9 (Q7NHL9_GLOVI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	glr2516

Organism

Gloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP]

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter › Gloeobacter violaceus

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 SAAS SAAS002569
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	54	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q7NHL9 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 438D4B3EFB472776	FASTA	221	24,210
	10 20 30 40 50 60 MGLFNKQVQM PTTAQALPGR AQRMPVSVPH HVNGRPLQPP FPQGTEQAMF GMGCFWGAER 70 80 90 100 110 120 VFWQAEGVYT TAVGYAAGLT PNPTYREVCS GMTGHNEVVL VVFDPRVISY ERLLQIFWEN 130 140 150 160 170 180 HDPTQGMRQG NDAGTQYRSG IYCSTPEQKQ IAEASRAAYQ QRLTAAGLGR ITTEVLDAPE 190 200 210 220 FYYAEDYHQQ YLSKNPGGYC GLGGTGVACP VGALESRPTA P

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC90457.1.
RefSeq	NP_925462.1. NC_005125.1.
3D structure databases
HSSP	HSSP built from PDB template 1FVA based on UniProtKB P54149.
ProteinModelPortal	Q7NHL9.
SMR	Q7NHL9. Positions 15-210.
ModBase	Search...
Protein-protein interaction databases
STRING	251221.glr2516.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC90457; BAC90457; BAC90457.
GeneID	2600917.
KEGG	gvi:glr2516.
PATRIC	22044513. VBIGloVio86258_2555.
Phylogenomic databases
HOGENOM	HOG000263862.
KO	K07304.
OMA	SAIYCTT.
ProtClustDB	PRK00058.
Enzyme and pathway databases
BioCyc	GVIO251221:GH9A-2565-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7NHL9_GLOVI

Accession

Primary (citable) accession number: Q7NHL9

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)