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Q7NH89 (RNC_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:glr2648
OrganismGloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP]
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000416605

Regions

Domain14 – 142129RNase III
Domain170 – 23566DRBM

Sites

Active site601 Potential
Active site1311 By similarity
Metal binding561Magnesium By similarity
Metal binding1281Magnesium By similarity
Metal binding1311Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7NH89 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 2931B2459D7CDD64

FASTA24226,473
        10         20         30         40         50         60 
MAESALTPLR LAQLRRFAAR FALSEPEALS WELLHRALIH PSWSAQEGGE DNDRLEFLGD 

        70         80         90        100        110        120 
EILRLLAAEF LYRADPELTV GEMTAVRSVL VSDVALAELA EGYDLGEFLV VGRSASGDER 

       130        140        150        160        170        180 
GRITRLADGF EAVIGALYLS TGDLGLIRPW LLPHLAHLAE SVMADPTRGN HKSALQELTQ 

       190        200        210        220        230        240 
KLAAGELPEY RLVDPGPPFR YEVWALGRLW GSGEGPSKKL AQQRAARGAY AALRSAFDTA 


LQ 

« Hide

References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000045 Genomic DNA. Translation: BAC90589.1.
RefSeqNP_925594.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NH89.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING251221.gvip371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC90589; BAC90589; BAC90589.
GeneID2601049.
KEGGgvi:gvip371.
PATRIC22044777. VBIGloVio86258_2685.

Phylogenomic databases

KOK03685.
OMAISMEANY.
OrthoDBEOG6T1WVS.
ProtClustDBCLSK423155.

Enzyme and pathway databases

BioCycGVIO251221:GH9A-2681-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_GLOVI
AccessionPrimary (citable) accession number: Q7NH89
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: December 15, 2003
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families