Q7NFK0 (PPNK2_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2
Short name=Poly(P)/ATP NAD kinase 2
EC=2.7.1.23

Gene names

Name:	ppnK2
Ordered Locus Names:	gll3525

Organism

Gloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP]

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter › Gloeobacter violaceus

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	NAD metabolic process Inferred from electronic annotation. Source: InterPro NADP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP-Rule MF_00361		PRO_0000229642

Sequences

	Sequence		Length	Mass (Da)
	Q7NFK0 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 99235657C6FCB72F	FASTA	309	33,606
	10 20 30 40 50 60 MMALPKAGII FNDIKPAAAR AAAELTEKFQ DAGYRVYQTT GWGGILGFPR PDSPVCHTPI 70 80 90 100 110 120 DRLAAEGFDE AMPFAIVLGG DGTVLAAARQ VAPFDIPLLT INTGHMGFLT EGYLNQIHPA 130 140 150 160 170 180 IDTLLAGQYA LEDRSMIEVR VFRDERLIWE ALALNEAVLH KEPLSGICHF EVAIGRHNIV 190 200 210 220 230 240 DIAADGVIVA TPTGSTAYAL SAGGPVITPD VQVLQLIPIC PHSLAARGLV FADTESLVVH 250 260 270 280 290 300 PPTNHQHLIL SLDGNSGCYI WPGDQVRIRR ARYRTRLIRL QPPEFFALLR EKLGWGLPHI AKPLSVELP

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC91466.1.
RefSeq	NP_926471.1. NC_005125.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	251221.gll3525.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC91466; BAC91466; BAC91466.
GeneID	2601929.
KEGG	gvi:gll3525.
PATRIC	22046541. VBIGloVio86258_3558.
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HOG000227222.
KO	K00858.
OMA	FANPDQH.
ProtClustDB	PRK02649.
Enzyme and pathway databases
BioCyc	GVIO251221:GH9A-3575-MONOMER.
Family and domain databases
Gene3D	2.60.200.30. 1 hit. 3.40.50.10330. 1 hit.
HAMAP	MF_00361. NAD_kinase.
InterPro	IPR017438. ATP-NAD_kinase_dom_1. IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. PolyP/ATP_NADK_prd. [Graphical view]
PANTHER	PTHR20275. PTHR20275. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPNK2_GLOVI

Accession

Primary (citable) accession number: Q7NFK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	December 15, 2003
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program