Reviewed, UniProtKB/Swiss-Prot Q7NFJ5 (GCST_GLOVI)

Names and origin

Protein names

Recommended name:
    Aminomethyltransferase
    EC=2.1.2.10
Alternative name(s):
    Glycine cleavage system T protein

Gene names

Name:	gcvT
Ordered Locus Names:	glr3530

Organism

Gloeobacter violaceus [Complete proteome] [HAMAP]

Taxonomic identifier

33072 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity.
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.
Sequence similarities	Belongs to the gcvT family.

Ontologies

Keywords
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Aminomethyltransferase HAMAP MF_00259		PRO_0000122560

Sequences

	Sequence		Length	Mass (Da)
	Q7NFJ5-1 [UniParc]. Last modified February 15, 2005. Version 2. Checksum: 7857B9A1F3FDDD61	FASTA	359	39,569
	10 20 30 40 50 60 MSDLKRTPLC AQHLQLGARL VPFGGWEMPL QYSTLTREHR AVRTAVGLFD ISHMGKYTLS 70 80 90 100 110 120 GPDVLAQIQR LVPSDLARLQ PGQAQYTVLL NEQAGIIDDL IFYCRSPEHW VVIVNGATND 130 140 150 160 170 180 KDRRWLAEHL QGVHFDDLTG THTLLALQGP AAVETLQPLV DIDLARLGRF EHAQVSLAGK 190 200 210 220 230 240 PAFLARTGYT GEDGFEIMSL EPEGIALWQS LTAAGVPPCG LGARDTLRLE AAMHLYGQDM 250 260 270 280 290 300 DESTTPLEAS LGWVIDWDKP DYFGREILLA QKAQGTERRL VGLTVEGRQI ARHGYGLFDG 310 320 330 340 350 EQQVGVVTSG TLTPTVDRPI ALAYVGKPFA PIGSRLEVDI RGRRAMATVV KRPFYRRAL

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000045 Genomic DNA. Translation: BAC91471.1. Different initiation.
RefSeq	NP_926476.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2601934.
GenomeReviews	Gene locus glr3530 in contig BA000045_GR.
KEGG	gvi:glr3530.
NMPDR	fig|251221.1.peg.3530.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7NFJ5.
Enzyme and pathway databases
BioCyc	GVIO251221:GLR3530-MON.
BRENDA	2.1.2.10. 276183.
Family and domain databases
HAMAP	MF_00259. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. gcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GCST_GLOVI

Accession

Primary (citable) accession number: Q7NFJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	January 20, 2009
This is version 31 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)