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Q7NFJ5 (GCST_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aminomethyltransferase
EC=2.1.2.10
Alternative name(s):
Glycine cleavage system T protein
Gene names
Name:gcvT
Ordered Locus Names:glr3530
OrganismGloeobacter violaceus (strain PCC 7421)
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Sequence similarities

Belongs to the GcvT family.

Sequence caution

The sequence BAC91471.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionAminotransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycine catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular functionaminomethyltransferase activity

Inferred from electronic annotation. Source: EC

transaminase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Aminomethyltransferase HAMAP MF_00259
PRO_0000122560

Sequences

Sequence LengthMass (Da)Tools
Q7NFJ5 [UniParc].

Last modified February 15, 2005. Version 2.
Checksum: 7857B9A1F3FDDD61

FASTA35939,569
        10         20         30         40         50         60 
MSDLKRTPLC AQHLQLGARL VPFGGWEMPL QYSTLTREHR AVRTAVGLFD ISHMGKYTLS 

        70         80         90        100        110        120 
GPDVLAQIQR LVPSDLARLQ PGQAQYTVLL NEQAGIIDDL IFYCRSPEHW VVIVNGATND 

       130        140        150        160        170        180 
KDRRWLAEHL QGVHFDDLTG THTLLALQGP AAVETLQPLV DIDLARLGRF EHAQVSLAGK 

       190        200        210        220        230        240 
PAFLARTGYT GEDGFEIMSL EPEGIALWQS LTAAGVPPCG LGARDTLRLE AAMHLYGQDM 

       250        260        270        280        290        300 
DESTTPLEAS LGWVIDWDKP DYFGREILLA QKAQGTERRL VGLTVEGRQI ARHGYGLFDG 

       310        320        330        340        350 
EQQVGVVTSG TLTPTVDRPI ALAYVGKPFA PIGSRLEVDI RGRRAMATVV KRPFYRRAL

« Hide

References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000045 Genomic DNA. Translation: BAC91471.1. Different initiation.
RefSeqNP_926476.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NFJ5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2601934.
GenomeReviewsGene locus glr3530 in contig BA000045_GR.
KEGGgvi:glr3530.
NMPDRfig|251221.1.peg.3530.
PATRIC22046551. VBIGloVio86258_3563.

Phylogenomic databases

HOGENOMHBG299834.
PhylomeDBQ7NFJ5.

Enzyme and pathway databases

BioCycGVIO251221:GLR3530-MONOMER.

Family and domain databases

HAMAPMF_00259. GcvT.
[Tree]
InterProIPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR006223. GcvT.
IPR022903. NH2_Me_Trfase.
[Graphical view]
KOK00605.
PANTHERPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. GcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGCST_GLOVI
AccessionPrimary (citable) accession number: Q7NFJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: January 25, 2012
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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