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Q7NEN0 (Q7NEN0_GLOVI) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetylornithine aminotransferase HAMAP-Rule MF_01107

Short name=ACOAT HAMAP-Rule MF_01107
EC=2.6.1.11 HAMAP-Rule MF_01107
Gene names
Name:argD HAMAP-Rule MF_01107
Ordered Locus Names:glr3849 EMBL BAC91790.1
OrganismGloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP] EMBL BAC91790.1
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter

Protein attributes

Sequence length439 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. HAMAP-Rule MF_01107

Cofactor

Binds 1 pyridoxal phosphate per subunit By similarity. HAMAP-Rule MF_01107

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4. HAMAP-Rule MF_01107

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01107

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01107.

Miscellaneous

May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis By similarity. HAMAP-Rule MF_01107

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. HAMAP-Rule MF_01107

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region260 – 2634Pyridoxal phosphate binding By similarity HAMAP-Rule MF_01107

Sites

Binding site1651Pyridoxal phosphate; via carbonyl oxygen By similarity HAMAP-Rule MF_01107
Binding site1681N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3161N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3171Pyridoxal phosphate By similarity HAMAP-Rule MF_01107

Amino acid modifications

Modified residue2891N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01107

Sequences

Sequence LengthMass (Da)Tools
Q7NEN0 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: C5BB680D1D21ED14

FASTA43946,990
        10         20         30         40         50         60 
MLSLPTKEAS LPRVPRLVGP LPGPRAQALI ARDEAVTSPS YTRGYPLVAA RGEGCMLEDV 

        70         80         90        100        110        120 
DGNVFLDLTA GIAVTATGHA HPVVVRAIQE QAANLLHMSG TDFYYEPMAE LAEALCERAP 

       130        140        150        160        170        180 
FPTAAGRPRA RVFFSNSGAE SNEGALKLAR YYTGRQQVVA FLGAFHGRTY GAMSLTGSRA 

       190        200        210        220        230        240 
VQRQGFGPLV PGISHIPYGT HASLDYLEDK LFPAVLPPEE IAAIVVESIQ GEGGYIVPED 

       250        260        270        280        290        300 
GFHERIRQIC TRHGILMVVD EVQAGMGRTG KLFAIEHWGV QPDIVTLAKG IASGLPLGAI 

       310        320        330        340        350        360 
LSRPEIMTWP AGSHATTFGG NPVACAAANA TLKLLEAGLI ENAERMGRVL QAGLGQLADR 

       370        380        390        400        410        420 
FSFVSASRGK GLMVAVDLFD AAGNLDRERR DQIVDLAFYR GLLLLGCGKA AIRFCPPLVI 

       430 
DADQVRVALD ILRQIFEEQ 

« Hide

References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421 EMBL BAC91790.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000045 Genomic DNA. Translation: BAC91790.1.
RefSeqNP_926795.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NEN0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING251221.glr3849.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC91790; BAC91790; BAC91790.
GeneID2602252.
KEGGgvi:glr3849.
PATRIC22047201. VBIGloVio86258_3884.

Phylogenomic databases

HOGENOMHOG000020206.
KOK00823.
OMAVMCDFFA.
OrthoDBEOG6QVRHN.
PhylomeDBQ7NEN0.

Enzyme and pathway databases

BioCycGVIO251221:GH9A-3899-MONOMER.
UniPathwayUPA00068; UER00109.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01107. ArgD_aminotrans_3.
InterProIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR004636. Trfase_AcOrn/SuccOrn_fam.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7NEN0_GLOVI
AccessionPrimary (citable) accession number: Q7NEN0
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)