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Q7NEN0

- Q7NEN0_GLOVI

UniProt

Q7NEN0 - Q7NEN0_GLOVI

Protein

Acetylornithine aminotransferase

Gene

argD

Organism
Gloeobacter violaceus (strain PCC 7421)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.UniRule annotation

    Cofactori

    Binds 1 pyridoxal phosphate per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei165 – 1651Pyridoxal phosphate; via carbonyl oxygenUniRule annotation
    Binding sitei168 – 1681N2-acetyl-L-ornithineUniRule annotation
    Binding sitei316 – 3161N2-acetyl-L-ornithineUniRule annotation
    Binding sitei317 – 3171Pyridoxal phosphateUniRule annotation

    GO - Molecular functioni

    1. N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    AminotransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesisUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciGVIO251221:GH9A-3899-MONOMER.
    UniPathwayiUPA00068; UER00109.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylornithine aminotransferaseUniRule annotation (EC:2.6.1.11UniRule annotation)
    Short name:
    ACOATUniRule annotation
    Gene namesi
    Name:argDUniRule annotation
    Ordered Locus Names:glr3849Imported
    OrganismiGloeobacter violaceus (strain PCC 7421)Imported
    Taxonomic identifieri251221 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter
    ProteomesiUP000000557: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei289 – 2891N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi251221.glr3849.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7NEN0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni260 – 2634Pyridoxal phosphate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000020206.
    KOiK00823.
    OMAiVMCDFFA.
    OrthoDBiEOG6QVRHN.
    PhylomeDBiQ7NEN0.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    HAMAPiMF_01107. ArgD_aminotrans_3.
    InterProiIPR004636. AcOrn/SuccOrn_fam.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7NEN0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSLPTKEAS LPRVPRLVGP LPGPRAQALI ARDEAVTSPS YTRGYPLVAA    50
    RGEGCMLEDV DGNVFLDLTA GIAVTATGHA HPVVVRAIQE QAANLLHMSG 100
    TDFYYEPMAE LAEALCERAP FPTAAGRPRA RVFFSNSGAE SNEGALKLAR 150
    YYTGRQQVVA FLGAFHGRTY GAMSLTGSRA VQRQGFGPLV PGISHIPYGT 200
    HASLDYLEDK LFPAVLPPEE IAAIVVESIQ GEGGYIVPED GFHERIRQIC 250
    TRHGILMVVD EVQAGMGRTG KLFAIEHWGV QPDIVTLAKG IASGLPLGAI 300
    LSRPEIMTWP AGSHATTFGG NPVACAAANA TLKLLEAGLI ENAERMGRVL 350
    QAGLGQLADR FSFVSASRGK GLMVAVDLFD AAGNLDRERR DQIVDLAFYR 400
    GLLLLGCGKA AIRFCPPLVI DADQVRVALD ILRQIFEEQ 439
    Length:439
    Mass (Da):46,990
    Last modified:December 15, 2003 - v1
    Checksum:iC5BB680D1D21ED14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000045 Genomic DNA. Translation: BAC91790.1.
    RefSeqiNP_926795.1. NC_005125.1.

    Genome annotation databases

    EnsemblBacteriaiBAC91790; BAC91790; BAC91790.
    GeneIDi2602252.
    KEGGigvi:glr3849.
    PATRICi22047201. VBIGloVio86258_3884.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000045 Genomic DNA. Translation: BAC91790.1 .
    RefSeqi NP_926795.1. NC_005125.1.

    3D structure databases

    ProteinModelPortali Q7NEN0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 251221.glr3849.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC91790 ; BAC91790 ; BAC91790 .
    GeneIDi 2602252.
    KEGGi gvi:glr3849.
    PATRICi 22047201. VBIGloVio86258_3884.

    Phylogenomic databases

    HOGENOMi HOG000020206.
    KOi K00823.
    OMAi VMCDFFA.
    OrthoDBi EOG6QVRHN.
    PhylomeDBi Q7NEN0.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00109 .
    BioCyci GVIO251221:GH9A-3899-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    HAMAPi MF_01107. ArgD_aminotrans_3.
    InterProi IPR004636. AcOrn/SuccOrn_fam.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 7421Imported.

    Entry informationi

    Entry nameiQ7NEN0_GLOVI
    AccessioniPrimary (citable) accession number: Q7NEN0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.UniRule annotation

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3