Reviewed, UniProtKB/Swiss-Prot Q7NEK3 (HEM6_GLOVI)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen 3 oxidase, aerobic
    EC=1.3.3.3
Alternative name(s):
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase

Gene names

Name:	hemF
Ordered Locus Names:	gll3876

Organism

Gloeobacter violaceus [Complete proteome] [HAMAP]

Taxonomic identifier

33072 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 289	289	Coproporphyrinogen 3 oxidase, aerobic		PRO_0000109898

Sequences

	Sequence		Length	Mass (Da)
	Q7NEK3-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 36285EE9D7B1AB78	FASTA	289	33,577
	10 20 30 40 50 60 MQSLQDNITS RLEAVDGEGR FVEDLWEREE GGGGRSRILT EGRVFERAGI GFSEVHGSHL 70 80 90 100 110 120 PPSILQQRPE AEGHPFYVTG TSMVLHPRNP YVPTVHLNYR YFEAGPVWWF GGGADLTPYY 130 140 150 160 170 180 GFVEDAAHFH ATLKAACDAH DPEYYPRFKK WCDEYFYLKH RQEPRGVGGI FFDYVQGDWE 190 200 210 220 230 240 KIFAFAQSCG NAFLPAYLPI VERRHTLPYA ERERNFQLYR RGRYVEFNLV WDRGTIFGLQ 250 260 270 280 TNGRIESILM SMPPLVRWEY NYRPEPGTAE AELYEVFLVP QDWASQAKR

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000045 Genomic DNA. Translation: BAC91817.1.
RefSeq	NP_926822.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2602279.
GenomeReviews	Gene locus gll3876 in contig BA000045_GR.
KEGG	gvi:gll3876.
NMPDR	fig|251221.1.peg.3876.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7NEK3.
Enzyme and pathway databases
BioCyc	GVIO251221:GLL3876-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_GLOVI

Accession

Primary (citable) accession number: Q7NEK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	December 15, 2003
Last modified:	November 4, 2008
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)