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Q7NE10 (SPEA_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:gll4070
OrganismGloeobacter violaceus (strain PCC 7421) [Reference proteome] [HAMAP]
Taxonomic identifier251221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacter

Protein attributes

Sequence length644 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 644644Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149963

Regions

Region282 – 29211Substrate-binding Potential

Amino acid modifications

Modified residue1001N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7NE10 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: B70B2C69C7B352A2

FASTA64472,694
        10         20         30         40         50         60 
MQDWTIEDSA ELYQIHGWGE PYFKINDKGH VAVMPRGEGN GEIDLFHLVQ DIQKRGLNMP 

        70         80         90        100        110        120 
MLIRFSDILA DRIARLNACF VEAIREYDYP GIYKGVYPVK VNQQRHVVEE VVEFGRPFQY 

       130        140        150        160        170        180 
GLEAGSKPEL LIALATLKTP GALIICNGYK DSEYIETALL AQRLGHTPFV VIERFHELTL 

       190        200        210        220        230        240 
LIEAAQKLGI RPLIGVRAKL TARGIGRWGD STGDRAKFGL SAGEIMEVVA QLKAADLLSS 

       250        260        270        280        290        300 
LQLLHFHIGS QISAINVIKT ALREASCVYV ELAQMGAPMQ YCDVGGGLAI DYDGSKTNFR 

       310        320        330        340        350        360 
ASKNYNMQEY AYDVVAAFQD ACRTKNVPVP TLVSESGRAI TSHQSVLVFD VMGVSHLQFG 

       370        380        390        400        410        420 
EPEPPARNEH SIIRNLYETY TQITPDNVQE AFNDASQFKE EALSLFALGY LGLGERARAE 

       430        440        450        460        470        480 
RLYWGCCEKI LNLVRELDYI PDELADLEKN MASTYYCNFS VFQSAPDSWA IDQLFPIMPI 

       490        500        510        520        530        540 
HRLDEEPKAR GTLADLTCDS DGKIDQFIDL RDVKGVLELH PVRPEEPYYL GMFLNGAYQE 

       550        560        570        580        590        600 
ILGDMHNLFG DTNTVHIHLA SDEPGEQSYR LEHVVKGDTM TEVLKYVQYD HEAMLESIRR 

       610        620        630        640 
ETEQALRERR ITLSESRLLL QHYERSLSGY TYLTNELQVE LAAR 

« Hide

References

[1]"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids."
Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S.
DNA Res. 10:137-145(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7421.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000045 Genomic DNA. Translation: BAC92011.1.
RefSeqNP_927016.1. NC_005125.1.

3D structure databases

ProteinModelPortalQ7NE10.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING251221.gll4070.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC92011; BAC92011; BAC92011.
GeneID2602453.
KEGGgvi:gll4070.
PATRIC22047639. VBIGloVio86258_4102.

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycGVIO251221:GH9A-4121-MONOMER.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_GLOVI
AccessionPrimary (citable) accession number: Q7NE10
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families