Q7NDF6 (SYR_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase
EC=6.1.1.19

Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	glr4279

Organism

Gloeobacter violaceus (strain PCC 7421)

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW arginine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 601	601	Arginine--tRNA ligase HAMAP MF_00123		PRO_0000151562
Regions
	Motif	135 – 145	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q7NDF6 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: C48DDEBD5F9B419A	FASTA	601	66,957
	10 20 30 40 50 60 MTALSLQQQL AESIYTALGT AFEAGQLGQL TQLPPRQSVV VEKPKVPEHG DYATPVAMSL 70 80 90 100 110 120 AKPCRLAPLA IAEAIASYLA SDEIGVEVAK PGFINLRLGH RFVAVELQNI LELKGDYGRT 130 140 150 160 170 180 VPQQPERILL EFVSANPTGP LHLGHGRWAA LGSSLERILQ FAGYTVDSEF YINDAGNQMQ 190 200 210 220 230 240 LLGLSLKQRY LQVLGEAVEL PDGGYKGSYL KELAEQLVAD KGDSLGGEPV EWFSAYAEGR 250 260 270 280 290 300 LLEQQKITLQ QFRTEFDRWY SERSLHCAGA IEAALADLEA RGMLYRAARS RQEQSGEITG 310 320 330 340 350 360 RSKKVQAPAA FEEEDGGGEA LFFKAADFGD EMDRVVKRAD GNTTYLAADI AYHWDKYQRG 370 380 390 400 410 420 YGRLINIWGA DHHGYVPRMK AVAQALGHPA DSLEILIGQM VRLFKTNPET GQKEEMRMSK 430 440 450 460 470 480 RRGELVSVDD LIEEVGVDAG RWFLLSQSLN TTVNFDLDLA QSEKFDNPVF YVQYNHARCC 490 500 510 520 530 540 SILRKAPERG MPILERFEFL KPDGGLWLET PQERTLALRL LAAPDEYRFA AVDRTPQRLT 550 560 570 580 590 600 QYAYDLASDV SQFYEHCPIL PPLAENLEPA LRYARLGLVV ATRQVLATTL TLLGIEPRES M

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC92220.1.
RefSeq	NP_927225.1. NC_005125.1.
3D structure databases
ProteinModelPortal	Q7NDF6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2602682.
GenomeReviews	Gene locus glr4279 in contig BA000045_GR.
NMPDR	fig|251221.1.peg.4279.
PATRIC	22048051. VBIGloVio86258_4307.
Phylogenomic databases
HOGENOM	HBG695395.
OMA	FDVYFHE.
PhylomeDB	Q7NDF6.
ProtClustDB	CLSK423190.
Enzyme and pathway databases
BioCyc	GVIO251221:GLR4279-MONOMER.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 2 hits. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_GLOVI

Accession

Primary (citable) accession number: Q7NDF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program