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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Gloeobacter violaceus (strain PCC 7421)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:glr4279
OrganismiGloeobacter violaceus (strain PCC 7421)
Taxonomic identifieri251221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacteraceaeGloeobacter
Proteomesi
  • UP000000557 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515621 – 601Arginine--tRNA ligaseAdd BLAST601

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi251221.gvip558.

Structurei

3D structure databases

ProteinModelPortaliQ7NDF6.
SMRiQ7NDF6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi135 – 145"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
InParanoidiQ7NDF6.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.
PhylomeDBiQ7NDF6.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7NDF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTALSLQQQL AESIYTALGT AFEAGQLGQL TQLPPRQSVV VEKPKVPEHG
60 70 80 90 100
DYATPVAMSL AKPCRLAPLA IAEAIASYLA SDEIGVEVAK PGFINLRLGH
110 120 130 140 150
RFVAVELQNI LELKGDYGRT VPQQPERILL EFVSANPTGP LHLGHGRWAA
160 170 180 190 200
LGSSLERILQ FAGYTVDSEF YINDAGNQMQ LLGLSLKQRY LQVLGEAVEL
210 220 230 240 250
PDGGYKGSYL KELAEQLVAD KGDSLGGEPV EWFSAYAEGR LLEQQKITLQ
260 270 280 290 300
QFRTEFDRWY SERSLHCAGA IEAALADLEA RGMLYRAARS RQEQSGEITG
310 320 330 340 350
RSKKVQAPAA FEEEDGGGEA LFFKAADFGD EMDRVVKRAD GNTTYLAADI
360 370 380 390 400
AYHWDKYQRG YGRLINIWGA DHHGYVPRMK AVAQALGHPA DSLEILIGQM
410 420 430 440 450
VRLFKTNPET GQKEEMRMSK RRGELVSVDD LIEEVGVDAG RWFLLSQSLN
460 470 480 490 500
TTVNFDLDLA QSEKFDNPVF YVQYNHARCC SILRKAPERG MPILERFEFL
510 520 530 540 550
KPDGGLWLET PQERTLALRL LAAPDEYRFA AVDRTPQRLT QYAYDLASDV
560 570 580 590 600
SQFYEHCPIL PPLAENLEPA LRYARLGLVV ATRQVLATTL TLLGIEPRES

M
Length:601
Mass (Da):66,957
Last modified:December 15, 2003 - v1
Checksum:iC48DDEBD5F9B419A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000045 Genomic DNA. Translation: BAC92220.1.
RefSeqiNP_927225.1. NC_005125.1.
WP_011144263.1. NC_005125.1.

Genome annotation databases

EnsemblBacteriaiBAC92220; BAC92220; BAC92220.
GeneIDi2602682.
KEGGigvi:gvip558.
PATRICifig|251221.4.peg.4307.

Similar proteinsi

Entry informationi

Entry nameiSYR_GLOVI
AccessioniPrimary (citable) accession number: Q7NDF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: August 30, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families