Q7NCK4 (COMB_GLOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	gll2974

Organism

Gloeobacter violaceus (strain PCC 7421)

Taxonomic identifier

251221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Gloeobacteria › Gloeobacterales › Gloeobacter

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081469

Sequences

	Sequence		Length	Mass (Da)
	Q7NCK4 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: E0C52D8038533C8E	FASTA	236	24,811
	10 20 30 40 50 60 MQVSVFHTPE LVPEGTPDCA VAVDVLRATS TIATALANGA TAVQVYADLE ALGAAAAGYP 70 80 90 100 110 120 REDILRGGER GGKQVEGFDF GNSPLYCTSE RVAGKRIFMS TTNGTRTLER IRHAPVVLTA 130 140 150 160 170 180 ALVNVGFVAR YIRSQAFETV WVVGSGWQGN FSLEDTVCAG ALVEQLGGAA NDEAVAAAAL 190 200 210 220 230 FDTWEGDLIE LLERASHGQR LLKLGLLDDI VYCAALDTVS ALPRQTAAGV LVQGMA

References

[1]

"Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids." Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T., Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M., Tabata S. DNA Res. 10:137-145(2003) [PubMed: 14621292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7421.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000045 Genomic DNA. Translation: BAC90915.1.
RefSeq	NP_925920.1. NC_005125.1.
3D structure databases
ProteinModelPortal	Q7NCK4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2601375.
GenomeReviews	Gene locus gll2974 in contig BA000045_GR.
KEGG	gvi:gll2974.
NMPDR	fig|251221.1.peg.2974.
PATRIC	22045417. VBIGloVio86258_3002.
Phylogenomic databases
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	Q7NCK4.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	GVIO251221:GLL2974-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_GLOVI

Accession

Primary (citable) accession number: Q7NCK4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 2, 2004
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program