Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q7NBG7 (PGK_MYCGA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:MYCGA3120
ORF Names:MGA_1187
OrganismMycoplasma gallisepticum (strain R(low / passage 15 / clone 2)) [Complete proteome] [HAMAP]
Taxonomic identifier710127 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length413 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 413413Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145964

Regions

Nucleotide binding369 – 3724ATP By similarity
Region24 – 263Substrate binding By similarity
Region62 – 654Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1231Substrate By similarity
Binding site1651Substrate By similarity
Binding site2161ATP By similarity
Binding site3431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7NBG7 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: AA8838BB74C2020F

FASTA41345,525
        10         20         30         40         50         60 
MINYNKKTLK DVDLKDKTVI VRVDFNVPIK DNKVIDDTRI VQALDTIKYL IEQNCKIVLL 

        70         80         90        100        110        120 
SHLSRIKSLE DISSKKKSLR PVYENLKTKL NNVKFLEENV GYDVVEAVKQ LKHQEVLLLE 

       130        140        150        160        170        180 
NTRYNDVDNQ GEVVKKESKN SPELGRFWAS LADVFVNDAF GTSHRAHASN VGIAANISQS 

       190        200        210        220        230        240 
CIGFLVQKEL EALSKLTNNP QRPFVVILGG AKVSDKLKVI ESLLKSADQI LIGGGMVNTF 

       250        260        270        280        290        300 
NKAKGYHIGK SLFEPEMLET AKKILAEDKD NKIILATDQM VTKASTITDI KTAPAGKCVF 

       310        320        330        340        350        360 
AKDEAENEDF EALDIGDESI KTFKSYIAKA KSIFWNGPLG VFENPNYERG SYEIAKAISE 

       370        380        390        400        410 
SDSYSVIGGG DSAAAANQFK LADKFSFVST GGGASLTFME QTVLPGIEAI QSK 

« Hide

References

[1]"The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R(low / passage 15 / clone 2).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015450 Genomic DNA. Translation: AAP56662.1.
RefSeqNP_853094.1. NC_004829.2.

3D structure databases

ProteinModelPortalQ7NBG7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233150.MGA_1187.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP56662; AAP56662; MGA_1187.
GeneID1089644.
KEGGmga:MGA_1187.
PATRIC20008419. VBIMycGal115357_0346.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAFPVDYVT.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycMGAL710127:GC09-366-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_MYCGA
AccessionPrimary (citable) accession number: Q7NBG7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 15, 2003
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways