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Q7NBG7

- PGK_MYCGA

UniProt

Q7NBG7 - PGK_MYCGA

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateUniRule annotation
    Binding sitei123 – 1231SubstrateUniRule annotation
    Binding sitei165 – 1651SubstrateUniRule annotation
    Binding sitei216 – 2161ATPUniRule annotation
    Binding sitei343 – 3431ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi369 – 3724ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMGAL710127:GC09-366-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:MYCGA3120
    ORF Names:MGA_1187
    OrganismiMycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
    Taxonomic identifieri710127 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000001418: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 413413Phosphoglycerate kinasePRO_0000145964Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi233150.MGA_1187.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7NBG7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingUniRule annotation
    Regioni62 – 654Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiFPVDYVT.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7NBG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MINYNKKTLK DVDLKDKTVI VRVDFNVPIK DNKVIDDTRI VQALDTIKYL    50
    IEQNCKIVLL SHLSRIKSLE DISSKKKSLR PVYENLKTKL NNVKFLEENV 100
    GYDVVEAVKQ LKHQEVLLLE NTRYNDVDNQ GEVVKKESKN SPELGRFWAS 150
    LADVFVNDAF GTSHRAHASN VGIAANISQS CIGFLVQKEL EALSKLTNNP 200
    QRPFVVILGG AKVSDKLKVI ESLLKSADQI LIGGGMVNTF NKAKGYHIGK 250
    SLFEPEMLET AKKILAEDKD NKIILATDQM VTKASTITDI KTAPAGKCVF 300
    AKDEAENEDF EALDIGDESI KTFKSYIAKA KSIFWNGPLG VFENPNYERG 350
    SYEIAKAISE SDSYSVIGGG DSAAAANQFK LADKFSFVST GGGASLTFME 400
    QTVLPGIEAI QSK 413
    Length:413
    Mass (Da):45,525
    Last modified:December 15, 2003 - v1
    Checksum:iAA8838BB74C2020F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015450 Genomic DNA. Translation: AAP56662.1.
    RefSeqiNP_853094.1. NC_004829.2.

    Genome annotation databases

    EnsemblBacteriaiAAP56662; AAP56662; MGA_1187.
    GeneIDi1089644.
    KEGGimga:MGA_1187.
    PATRICi20008419. VBIMycGal115357_0346.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015450 Genomic DNA. Translation: AAP56662.1 .
    RefSeqi NP_853094.1. NC_004829.2.

    3D structure databases

    ProteinModelPortali Q7NBG7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 233150.MGA_1187.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP56662 ; AAP56662 ; MGA_1187 .
    GeneIDi 1089644.
    KEGGi mga:MGA_1187.
    PATRICi 20008419. VBIMycGal115357_0346.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi FPVDYVT.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci MGAL710127:GC09-366-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
      Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
      Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: R(low / passage 15 / clone 2).

    Entry informationi

    Entry nameiPGK_MYCGA
    AccessioniPrimary (citable) accession number: Q7NBG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3