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Q7NBC4

- UVRC_MYCGA

UniProt

Q7NBC4 - UVRC_MYCGA

Protein

UvrABC system protein C

Gene

uvrC

Organism
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 2 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nuclease

    Keywords - Biological processi

    DNA damage, DNA excision, DNA repair, SOS response

    Enzyme and pathway databases

    BioCyciMGAL710127:GC09-416-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:MYCGA3550
    ORF Names:MGA_1269
    OrganismiMycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
    Taxonomic identifieri710127 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000001418: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 592592UvrABC system protein CPRO_0000264915Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi233150.MGA_1269.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7NBC4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini14 – 9178GIY-YIGUniRule annotationAdd
    BLAST
    Domaini197 – 23236UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279960.
    KOiK03703.
    OMAiQTIASCV.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view]
    SUPFAMiSSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7NBC4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNFNLKQKLD LAPKKPGCYL WKNHLNEIIY IGKAKNIYKR VHQYFNGPKD    50
    LKTSKLVNEI FYVEFIEVNN ENEALLLEAN LIKKHKPRYN ILLKDNNGYP 100
    YILMTKEKYP RLIYTRNFDP KKGKHYGPFA SSEMKAYDLY NLLLKLFPLK 150
    NCFNKKGRKC EFYDLNLCMK ACTHEVSEAD YEVMKKKIDY FFHNGADQVL 200
    KDLKEKESIA SEKFDFEQAK KYLDLQKAIN LIFDKQIINL YSAKERIDVL 250
    AYQIKENVIC IVLFSYVSSQ LVSKNTICDF YYGEEQEVIT SYLSQYYKDN 300
    IKPKILYASL DQANATLLKD SLGIEIINPT SGKMNEIMSL ALQNVTNELS 350
    QKYDSLVKKE QRINLALDQL KKLIKVDKLN HLEVYDNSNL FNTDKVSAMI 400
    VFENNQFNKK KYRKYKIKDQ QALGDYHYMY EVIYRRLYQA LKNNFVDLPD 450
    LIILDGGKHQ VLAAKKAIVD LQIDKKINLI GLAKNNKHQT DKIVTFDLDE 500
    ISLDKSSALY FFLANLQEEV HKFAISFFRK TKAKSLYDSI LDQIKGLGKK 550
    RKQQLIEHFK TIDEIKKASI ASLSQVLPIE IAKKLKQKLD QS 592
    Length:592
    Mass (Da):69,238
    Last modified:December 12, 2006 - v2
    Checksum:iB2280A0F69033DCC
    GO

    Sequence cautioni

    The sequence AAP56705.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015450 Genomic DNA. Translation: AAP56705.2. Different initiation.
    RefSeqiNP_853137.3. NC_004829.2.

    Genome annotation databases

    EnsemblBacteriaiAAP56705; AAP56705; MGA_1269.
    GeneIDi1089683.
    KEGGimga:MGA_1269.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015450 Genomic DNA. Translation: AAP56705.2 . Different initiation.
    RefSeqi NP_853137.3. NC_004829.2.

    3D structure databases

    ProteinModelPortali Q7NBC4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 233150.MGA_1269.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP56705 ; AAP56705 ; MGA_1269 .
    GeneIDi 1089683.
    KEGGi mga:MGA_1269.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279960.
    KOi K03703.
    OMAi QTIASCV.

    Enzyme and pathway databases

    BioCyci MGAL710127:GC09-416-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
      Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
      Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: R(low / passage 15 / clone 2).

    Entry informationi

    Entry nameiUVRC_MYCGA
    AccessioniPrimary (citable) accession number: Q7NBC4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 70 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3