Reviewed, UniProtKB/Swiss-Prot Q7N9Y1 (UXUA_PHOLL)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	plu0170

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 395	395	Mannonate dehydratase HAMAP MF_00106		PRO_0000170679

Sequences

	Sequence		Length	Mass (Da)
	Q7N9Y1-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 7D7FBFE685E8559D	FASTA	395	45,317
	10 20 30 40 50 60 MEQTWRWFGP NDPVSLDDIR QAGATGIVTA LHHIPNGHIW NKDEILARKT LIENKGLIWS 70 80 90 100 110 120 VVESVPVHEE IKTRTGHYSQ WINNYKTSLK NLAECGIDTV CYNFMPVLDW TRTDLEYSLP 130 140 150 160 170 180 DGSKALRFDQ IAFAAFEIYI LKRPNAEADY TVEEQAQAKV YHDNMSAADI KKLTTNIIAG 190 200 210 220 230 240 LPGAEEGYTL AEFQAQLDRY KDITRDKLRE HLAYFLHQIV PVCEEYGLRL AIHPDDPPRP 250 260 270 280 290 300 ILGLPRIIST IEDIEWLTTI EPSPANGITM CTGSYGVRSD NDLVEIIKHY GNRIYFTHLR 310 320 330 340 350 360 STQREENSKT FHEATHLAGD VDMYNVVMEI LREEYRRKKV GDNRLIPMRP DHGHQIIDDL 370 380 390 KKQTNPGYSC IGRLKGLAEI RGLELGLRRA FFENK

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571859 Genomic DNA. Translation: CAE12465.1.
RefSeq	NP_927536.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2800119.
GenomeReviews	Gene locus plu0170 in contig BX470251_GR.
KEGG	plu:plu0170.
NMPDR	fig|243265.1.peg.160.
Organism-specific databases
PhotoList	plu0170.
CMR	Search...
Phylogenomic databases
HOGENOM	Q7N9Y1.
OMA	VHEEIKT.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU0170-MON.
BRENDA	4.2.1.8. 308689.
Family and domain databases
HAMAP	MF_00106. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_PHOLL

Accession

Primary (citable) accession number: Q7N9Y1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)