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Protein

HTH-type transcriptional regulator MalT

Gene

malT

Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.UniRule annotation

Enzyme regulationi

Activated by ATP and maltotriose, which are both required for DNA binding.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi39 – 46ATPUniRule annotation8
DNA bindingi856 – 875H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processCarbohydrate metabolism, Transcription, Transcription regulation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPLUM243265:G1GTE-470-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator MalTUniRule annotation
Alternative name(s):
ATP-dependent transcriptional activator MalTUniRule annotation
Gene namesi
Name:malTUniRule annotation
Ordered Locus Names:plu0471
OrganismiPhotorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaePhotorhabdus
Proteomesi
  • UP000002514 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001841661 – 904HTH-type transcriptional regulator MalTAdd BLAST904

Proteomic databases

PRIDEiQ7N976

Interactioni

Subunit structurei

Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.UniRule annotation

Protein-protein interaction databases

STRINGi243265.plu0471

Structurei

3D structure databases

ProteinModelPortaliQ7N976
SMRiQ7N976
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini832 – 897HTH luxR-typeUniRule annotationAdd BLAST66

Sequence similaritiesi

Belongs to the MalT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41061ZR Bacteria
COG2909 LUCA
HOGENOMiHOG000218261
KOiK03556
OMAiSDWVSNA
OrthoDBiPOG091H0FN0

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
Gene3Di1.10.10.10, 1 hit
1.25.40.10, 1 hit
HAMAPiMF_01247 HTH_type_MalT, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR011990 TPR-like_helical_dom_sf
IPR023768 Tscrpt_reg_HTH_MalT
IPR000792 Tscrpt_reg_LuxR_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00196 GerE, 1 hit
PRINTSiPR00038 HTHLUXR
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00622 HTH_LUXR_1, 1 hit
PS50043 HTH_LUXR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7N976-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIPSKLSRP VRLNNTVLRE RLLIRLNESS NYRLVLITSP AGYGKTTLVS
60 70 80 90 100
QWAAGQDNLG WYSLDESDNQ PERFASYLIA ALQQATQGHC VKSEVLAQKH
110 120 130 140 150
QYANLPALFA QLFIELSEWR RPIFLVIDDY HLIVNNMIHE AMRFFLRHQP
160 170 180 190 200
ENLTLTILSR NLPSLGVANL RVREQLLEID SQQLAFDYQE TQQFFDKRLT
210 220 230 240 250
TSLDADDCKR LCNEVAGWAT ALQLIALSAR QSCDAAELSA KRLSGINAGH
260 270 280 290 300
LSDYLVDEVL NQVGSSTREF LLRSSILRSM NDGLIVRLTG EENGQQRLEE
310 320 330 340 350
TERQGLFIQR MDDSGEWFRF HPLFASFLRQ RCQWEMALQL PELHRAAAEG
360 370 380 390 400
WLAQGYPGEA IHHALAAGDT AMLRDILLQH AWSLFNHSEL SLLEECMNAL
410 420 430 440 450
PYEQLLESPR LVLLQAWLAQ SQHRYSEVNT LLNQAEQALQ QKQIAIEPDL
460 470 480 490 500
LAEFDALRAQ VAMNSGKPEM ADKLAKQALA ALLPQNEYSR IVATSVEGEV
510 520 530 540 550
LHCRGELADA LARMQQTEQL ARRFHVHHYA LWALLQQSEI LLAQGYLQTA
560 570 580 590 600
YETQNKAFEL IREQHLEQLP MHEFLLRIRS QLLWCWSRLD EAEEAARRGL
610 620 630 640 650
EVLSNFQPQQ QLQCLTQLAK CSLTRGDIDN ARRYLARCEN LLSNGQYHRD
660 670 680 690 700
WRTNTDKLRV IIWQSMDDKS AAIRWLAQTE RPESVSNHFN QGQWRNIARA
710 720 730 740 750
QILLGLYDEA ESILDTLNQH ARELQLISDL NRNLLLCNLL YWHIGRKSEA
760 770 780 790 800
QSALIEALSL ANRTGFISHF VIEGELMAQQ LRQLIQLNTL SELELHRAQR
810 820 830 840 850
ILRDINRQHR HKFAHFDESF VTQLLTHPDV PELIRNSPLT QREWQVLGLI
860 870 880 890 900
YSGYSNDQIA AELDVATTTI KTHIRNLYQK LGIANRQEAI QQAQQLMQMM

GLGV
Length:904
Mass (Da):103,872
Last modified:December 15, 2003 - v1
Checksum:i84FC3A19038FF779
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571860 Genomic DNA Translation: CAE12766.1
RefSeqiWP_011144857.1, NC_005126.1

Genome annotation databases

EnsemblBacteriaiCAE12766; CAE12766; plu0471
KEGGiplu:plu0471

Similar proteinsi

Entry informationi

Entry nameiMALT_PHOLL
AccessioniPrimary (citable) accession number: Q7N976
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 15, 2003
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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