Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q7N955 (Q7N955_PHOLL) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138 EMBL CAE12789.1
Ordered Locus Names:plu0494
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP] EMBL CAE12789.1
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus ›

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 316208ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding135 – 19662ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2861Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2881Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
Q7N955 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: EFF08A52E3A080D5

FASTA42745,511
        10         20         30         40         50         60 
MNILIVGSGG REHALAWKAA QSPLADKIYV APGNAGTALE SNLENIDISA TDINGLLVFA 

        70         80         90        100        110        120 
QSHDIGLTIV GPEVPLVLGI VDAFQTAGLT IFGPTQAAAQ LEGSKAFTKD FLARHQIPTA 

       130        140        150        160        170        180 
AYQNFTAIEP ALAYLDKVGV PIVIKADGLA AGKGVIVAIT REEAQSAIKD MLAGNAFGDA 

       190        200        210        220        230        240 
GHRIVIEEFL TGEEASFIVM VDGKNVIPMA TSQDHKRIGD GDSGPNTGGM GAYSPAPVVT 

       250        260        270        280        290        300 
NEIHQRIMEE IIYPTVNGMA AEGHVYTGFL YAGLMISQNG EPKVIEFNCR FGDPETQPIM 

       310        320        330        340        350        360 
MRMRSDLVEL CLAGAKGELA GKTSDWDERP ALGVVLAAGG YPADYHKGDI IHGLPQQENE 

       370        380        390        400        410        420 
SSKVFHAGTA MKDNDVITAG GRVLCVTALG ETIIDAQKNA YQQAEEIEWN NCFYRKDIGY 


RAINRLK

« Hide

References

[1]"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens."
Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. expand/collapse author list , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F.
Nat. Biotechnol. 21:1307-1313(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TT01.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX571860 Genomic DNA. Translation: CAE12789.1.
RefSeqNP_927847.1. NC_005126.1.

3D structure databases

HSSPHSSP built from PDB template 1GSO based on UniProtKB P15640.
ProteinModelPortalQ7N955.
SMRQ7N955. Positions 1-425.
ModBaseSearch...

Protein-protein interaction databases

STRING243265.plu0494.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE12789; CAE12789; plu0494.
GeneID2800444.
KEGGplu:plu0494.
PATRIC20504499. VBIPhoLum48522_0535.

Organism-specific databases

GenoListplu0494.
CMRSearch...

Phylogenomic databases

HOGENOMHOG000033463.
KOK01945.
OMAMGAYTPL.
ProtClustDBPRK00885.

Enzyme and pathway databases

UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7N955_PHOLL
AccessionPrimary (citable) accession number: Q7N955
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info