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Q7N7H7

- GLSA_PHOLL

UniProt

Q7N7H7 - GLSA_PHOLL

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Protein
Glutaminase
Gene
glsA, plu1172
Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661Substrate By similarity
Binding sitei117 – 1171Substrate By similarity
Binding sitei161 – 1611Substrate By similarity
Binding sitei168 – 1681Substrate By similarity
Binding sitei192 – 1921Substrate By similarity
Binding sitei244 – 2441Substrate By similarity
Binding sitei262 – 2621Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:plu1172
OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002514: Chromosome

Organism-specific databases

GenoListiplu1172.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308GlutaminaseUniRule annotation
PRO_0000110615Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi243265.plu1172.

Structurei

3D structure databases

ProteinModelPortaliQ7N7H7.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7N7H7-1 [UniParc]FASTAAdd to Basket

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MSTTFSNTLL SDILRQVRPL IGQGKVANYI PALAEVPADN LAIAICTIDG    50
QIFHAGDAEK RFSIQSISKI LSLTLAMTRY QEQEIWQRVG QEPSGQPFNS 100
LVQLELEKGK PRNPFVNAGA LIVCDMLQSR LSAPKQRMLE VVRKLAGCPD 150
ICYDSKVARS EMEHSHRNAA IAYLMKSFGN FDNDVLAVLQ TYFHYCALKM 200
NCIELAKCFI YLANQGSTIG SEQQILSPRQ ARQINALMMT CGMYDGSGEF 250
AFRIGMPGKS GVGGGIVCVV PGEFTVTVWS PELDRSGNSL AGCAALELLA 300
DRVGRSVF 308
Length:308
Mass (Da):33,697
Last modified:December 15, 2003 - v1
Checksum:iC770535B62AE4D92
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571862 Genomic DNA. Translation: CAE13466.1.
RefSeqiNP_928484.1. NC_005126.1.

Genome annotation databases

EnsemblBacteriaiCAE13466; CAE13466; plu1172.
GeneIDi2801136.
KEGGiplu:plu1172.
PATRICi20506039. VBIPhoLum48522_1291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571862 Genomic DNA. Translation: CAE13466.1 .
RefSeqi NP_928484.1. NC_005126.1.

3D structure databases

ProteinModelPortali Q7N7H7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243265.plu1172.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE13466 ; CAE13466 ; plu1172 .
GeneIDi 2801136.
KEGGi plu:plu1172.
PATRICi 20506039. VBIPhoLum48522_1291.

Organism-specific databases

GenoListi plu1172.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TT01.

Entry informationi

Entry nameiGLSA_PHOLL
AccessioniPrimary (citable) accession number: Q7N7H7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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