Reviewed, UniProtKB/Swiss-Prot Q7N6Z9 (HEM6_PHOLL)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	plu1383

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen-III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333		PRO_0000109905

Sequences

	Sequence		Length	Mass (Da)
	Q7N6Z9-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: F5367536CB8BFD72	FASTA	302	35,141
	10 20 30 40 50 60 MNTPNINQIK SFFLSLQDEI CQQLEQIDGK EKFTEQCWQR EEGGGGRSRI MKEGTIFEQA 70 80 90 100 110 120 GANFSHVSGD MLPLSATAHR PELVGRHYQA MGVSLVIHPL NPYIPTSHAN VRFFIAEKEG 130 140 150 160 170 180 EAPVWWFGGG FDLTPYYGFK EDAIHWHTTA RNICRPYGED VYPKYKEWCD NYFYIKHRNE 190 200 210 220 230 240 ARGIGGLFYD DLNTPDFEHC FNFTQDIGKG FLSAYLPIVE KRKEILWGER ERQFQLYRRG 250 260 270 280 290 300 RYVEFNLVWD RGTLFGLQSG GRTESILMSM PPLARWEHDY HPEPESAEAA LYTDFLPAKN WI

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571863 Genomic DNA. Translation: CAE13676.1.
RefSeq	NP_928683.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2801361.
GenomeReviews	Gene locus plu1383 in contig BX470251_GR.
KEGG	plu:plu1383.
NMPDR	fig|243265.1.peg.1307.
Organism-specific databases
PhotoList	plu1383.
CMR	Search...
Phylogenomic databases
HOGENOM	Q7N6Z9.
OMA	VKAYLLD.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU1383-MON.
BRENDA	1.3.3.3. 308689.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. IPR018375. Coproporphyrinogen-3_ox_CS. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_PHOLL

Accession

Primary (citable) accession number: Q7N6Z9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)