Q7N6R1 (6PGL_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	plu1480

Organism

Photorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]

Taxonomic identifier

243265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000171136

Sequences

	Sequence		Length	Mass (Da)
	Q7N6R1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 5B09687ABA289EB0	FASTA	328	36,427
	10 20 30 40 50 60 MKQVVYTASP NSCQIHVWSL NNEGELSLIQ TVDVPGEVQP MVVSPDRKHL YVGIRPQFSI 70 80 90 100 110 120 VTYQIGSRGE LAQQGISSIP GSPTHISTDK QGRFLFSASY SYNNLSVSLI DDQGIVGEPV 130 140 150 160 170 180 QVIAGLQAPH SANIDWDNKQ LLVPCLKEDR VRIFEMAKEG YLTEKRAEEI TTAMGAGPRH 190 200 210 220 230 240 MAFHPNQQVI YCINELDSTV DVYRKWEKYR TVQTVDSLPA DLAGVRWSAD IHITPDGRHL 250 260 270 280 290 300 YTSERTSSLI SHFVISQDGS NLTLAGHYKT EIQPRGFAID HSGKYLIASG QKSDHISVSS 310 320 IDKYTGKLTE LTRYPVGKGP MWVTVLAL

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571864 Genomic DNA. Translation: CAE13773.1.
RefSeq	NP_928776.1. NC_005126.1.
3D structure databases
ProteinModelPortal	Q7N6R1.
SMR	Q7N6R1. Positions 1-327.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2801475.
GenomeReviews	Gene locus plu1480 in contig BX470251_GR.
KEGG	plu:plu1480.
NMPDR	fig|243265.1.peg.1400.
PATRIC	20506805. VBIPhoLum48522_1645.
Organism-specific databases
GenoList	plu1480.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG741123.
OMA	NIEGCHA.
PhylomeDB	Q7N6R1.
ProtClustDB	PRK11028.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU1480-MONOMER.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR011045. N2O_reductase_N. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KO	K07404.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
SUPFAM	SSF50974. N2O_reductase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_PHOLL

Accession

Primary (citable) accession number: Q7N6R1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program