Q7N6J4 (URK_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uridine kinase
EC=2.7.1.48

Alternative name(s):
Cytidine monophosphokinase
Uridine monophosphokinase

Gene names

Name:	udk
Ordered Locus Names:	plu1556

Organism

Photorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]

Taxonomic identifier

243265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + uridine = ADP + UMP. HAMAP MF_00551 ATP + cytidine = ADP + CMP. HAMAP MF_00551
Pathway	Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. HAMAP MF_00551 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. HAMAP MF_00551
Subcellular location	Cytoplasm By similarity HAMAP MF_00551.
Sequence similarities	Belongs to the uridine kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro uridine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Uridine kinase HAMAP MF_00551		PRO_1000017886
Regions
	Nucleotide binding	15 – 22	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7N6J4 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 9A8C028E7D5871F3	FASTA	213	24,488
	10 20 30 40 50 60 MADEAYQCTI VGISGASASG KSLIANTLYR ELRAQVGDHN IGIIPEDCYY KDQSDLSMEE 70 80 90 100 110 120 RYKTNYDHPS SMDHNLLFSH LQALKMGESI ELPQYDYVAH TRKPEAIHFA PKRVIILEGI 130 140 150 160 170 180 LLLTDKRLRQ EMDFSIFVDT PLDICLMRRI KRDVHERGRS LDSVIEQYHK TVRPMFLQFI 190 200 210 EPSKQYADII VPRGGKNRVA IDILKAKIGQ FCE

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571864 Genomic DNA. Translation: CAE13849.1.
RefSeq	NP_928847.1. NC_005126.1.
3D structure databases
HSSP	HSSP built from PDB template 1UFQ based on UniProtKB Q9BZX2.
ProteinModelPortal	Q7N6J4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2801551.
GenomeReviews	Gene locus plu1556 in contig BX470251_GR.
KEGG	plu:plu1556.
NMPDR	fig|243265.1.peg.1471.
PATRIC	20506983. VBIPhoLum48522_1734.
Organism-specific databases
GenoList	plu1556.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG527126.
OMA	DQTHLTM.
PhylomeDB	Q7N6J4.
ProtClustDB	PRK05480.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU1556-MONOMER.
Family and domain databases
HAMAP	MF_00551. Uridine_kinase. [Tree]
InterPro	IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view]
KO	K00876.
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00988. URIDINKINASE.
TIGRFAMs	TIGR00235. Udk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URK_PHOLL

Accession

Primary (citable) accession number: Q7N6J4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program