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Q7N621 (PNCB_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:plu1754
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205835

Sequences

Sequence LengthMass (Da)Tools
Q7N621 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: B1774889F728B768

FASTA40446,168
        10         20         30         40         50         60 
MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY ATELRHQVNM 

        70         80         90        100        110        120 
MADLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI SVTNGGQLAI HISGLWYEVI 

       130        140        150        160        170        180 
MWEVPLLALI SELIHRHHSP DNTVENAVNQ LRKLIKLFYQ HAENEGIDLS SFKLMDFGTR 

       190        200        210        220        230        240 
RRFSHRVQHA VVSELQQHFP YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS 

       250        260        270        280        290        300 
QREALQSWLK EYPNQLGIAL TDCITMDAFL RDFDAQFAKN YQGLRHDSGD PVQWGEKAIA 

       310        320        330        340        350        360 
HYQKLGIDPM TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTQLTCNI PGVKPLNIVI 

       370        380        390        400 
KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV KQAC 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571865 Genomic DNA. Translation: CAE14047.1.
RefSeqNP_929033.1. NC_005126.1.

3D structure databases

ProteinModelPortalQ7N621.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu1754.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE14047; CAE14047; plu1754.
GeneID2801749.
KEGGplu:plu1754.
PATRIC20507439. VBIPhoLum48522_1963.

Organism-specific databases

GenoListplu1754.
CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_PHOLL
AccessionPrimary (citable) accession number: Q7N621
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways