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Q7N621

- PNCB_PHOLL

UniProt

Q7N621 - PNCB_PHOLL

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, plu1754
Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:plu1754
OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002514: Chromosome

Organism-specific databases

GenoListiplu1754.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205835Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243265.plu1754.

Structurei

3D structure databases

ProteinModelPortaliQ7N621.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7N621-1 [UniParc]FASTAAdd to Basket

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MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY    50
ATELRHQVNM MADLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI 100
SVTNGGQLAI HISGLWYEVI MWEVPLLALI SELIHRHHSP DNTVENAVNQ 150
LRKLIKLFYQ HAENEGIDLS SFKLMDFGTR RRFSHRVQHA VVSELQQHFP 200
YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS QREALQSWLK 250
EYPNQLGIAL TDCITMDAFL RDFDAQFAKN YQGLRHDSGD PVQWGEKAIA 300
HYQKLGIDPM TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTQLTCNI 350
PGVKPLNIVI KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV 400
KQAC 404
Length:404
Mass (Da):46,168
Last modified:December 15, 2003 - v1
Checksum:iB1774889F728B768
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571865 Genomic DNA. Translation: CAE14047.1.
RefSeqiNP_929033.1. NC_005126.1.
WP_011146033.1. NC_005126.1.

Genome annotation databases

EnsemblBacteriaiCAE14047; CAE14047; plu1754.
GeneIDi2801749.
KEGGiplu:plu1754.
PATRICi20507439. VBIPhoLum48522_1963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571865 Genomic DNA. Translation: CAE14047.1 .
RefSeqi NP_929033.1. NC_005126.1.
WP_011146033.1. NC_005126.1.

3D structure databases

ProteinModelPortali Q7N621.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243265.plu1754.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE14047 ; CAE14047 ; plu1754 .
GeneIDi 2801749.
KEGGi plu:plu1754.
PATRICi 20507439. VBIPhoLum48522_1963.

Organism-specific databases

GenoListi plu1754.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TT01.

Entry informationi

Entry nameiPNCB_PHOLL
AccessioniPrimary (citable) accession number: Q7N621
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 15, 2003
Last modified: September 3, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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