Reviewed, UniProtKB/Swiss-Prot Q7N621 (PNCB_PHOLL)

Names and origin

Protein names

Recommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	plu1754

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_0000205835

Sequences

	Sequence		Length	Mass (Da)
	Q7N621-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: B1774889F728B768	FASTA	404	46,168
	10 20 30 40 50 60 MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY ATELRHQVNM 70 80 90 100 110 120 MADLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI SVTNGGQLAI HISGLWYEVI 130 140 150 160 170 180 MWEVPLLALI SELIHRHHSP DNTVENAVNQ LRKLIKLFYQ HAENEGIDLS SFKLMDFGTR 190 200 210 220 230 240 RRFSHRVQHA VVSELQQHFP YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS 250 260 270 280 290 300 QREALQSWLK EYPNQLGIAL TDCITMDAFL RDFDAQFAKN YQGLRHDSGD PVQWGEKAIA 310 320 330 340 350 360 HYQKLGIDPM TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTQLTCNI PGVKPLNIVI 370 380 390 400 KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV KQAC

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571865 Genomic DNA. Translation: CAE14047.1.
RefSeq	NP_929033.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2801749.
GenomeReviews	Gene locus plu1754 in contig BX470251_GR.
KEGG	plu:plu1754.
NMPDR	fig|243265.1.peg.1657.
Organism-specific databases
PhotoList	plu1754.
CMR	Search...
Phylogenomic databases
HOGENOM	Q7N621.
OMA	ALTDTFG.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU1754-MON.
BRENDA	2.4.2.11. 308689.
Family and domain databases
HAMAP	MF_00570. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. [Graphical view]
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_PHOLL

Accession

Primary (citable) accession number: Q7N621

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 5, 2005
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)