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Q7N621

- PNCB_PHOLL

UniProt

Q7N621 - PNCB_PHOLL

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:plu1754
    OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)
    Taxonomic identifieri243265 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
    ProteomesiUP000002514: Chromosome

    Organism-specific databases

    GenoListiplu1754.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 404404Nicotinate phosphoribosyltransferasePRO_0000205835Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243265.plu1754.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7N621.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    HOGENOMiHOG000284928.
    KOiK00763.
    OMAiQAVFHRY.
    OrthoDBiEOG6X10XB.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7N621-1 [UniParc]FASTAAdd to Basket

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    MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY    50
    ATELRHQVNM MADLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI 100
    SVTNGGQLAI HISGLWYEVI MWEVPLLALI SELIHRHHSP DNTVENAVNQ 150
    LRKLIKLFYQ HAENEGIDLS SFKLMDFGTR RRFSHRVQHA VVSELQQHFP 200
    YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS QREALQSWLK 250
    EYPNQLGIAL TDCITMDAFL RDFDAQFAKN YQGLRHDSGD PVQWGEKAIA 300
    HYQKLGIDPM TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTQLTCNI 350
    PGVKPLNIVI KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV 400
    KQAC 404
    Length:404
    Mass (Da):46,168
    Last modified:December 15, 2003 - v1
    Checksum:iB1774889F728B768
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571865 Genomic DNA. Translation: CAE14047.1.
    RefSeqiNP_929033.1. NC_005126.1.
    WP_011146033.1. NC_005126.1.

    Genome annotation databases

    EnsemblBacteriaiCAE14047; CAE14047; plu1754.
    GeneIDi2801749.
    KEGGiplu:plu1754.
    PATRICi20507439. VBIPhoLum48522_1963.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571865 Genomic DNA. Translation: CAE14047.1 .
    RefSeqi NP_929033.1. NC_005126.1.
    WP_011146033.1. NC_005126.1.

    3D structure databases

    ProteinModelPortali Q7N621.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243265.plu1754.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE14047 ; CAE14047 ; plu1754 .
    GeneIDi 2801749.
    KEGGi plu:plu1754.
    PATRICi 20507439. VBIPhoLum48522_1963.

    Organism-specific databases

    GenoListi plu1754.

    Phylogenomic databases

    eggNOGi COG1488.
    HOGENOMi HOG000284928.
    KOi K00763.
    OMAi QAVFHRY.
    OrthoDBi EOG6X10XB.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TT01.

    Entry informationi

    Entry nameiPNCB_PHOLL
    AccessioniPrimary (citable) accession number: Q7N621
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2005
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3