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Q7N577 (LUXC_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl-CoA reductase

EC=1.2.1.50
Gene names
Name:luxC
Ordered Locus Names:plu2079
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length480 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase By similarity.

Catalytic activity

A long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.

Pathway

Lipid metabolism; fatty acid reduction for biolumincescence.

Sequence similarities

Belongs to the LuxC family.

Ontologies

Keywords
   Biological processLuminescence
   LigandNADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processbioluminescence

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionacyl-CoA dehydrogenase activity

Inferred from electronic annotation. Source: InterPro

long-chain-fatty-acyl-CoA reductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 480480Acyl-CoA reductase
PRO_0000220198

Sequences

Sequence LengthMass (Da)Tools
Q7N577 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 48DC9106D75662BB

FASTA48054,815
        10         20         30         40         50         60 
MTKKISFIIN GQVEIFPESD DLVQSINFGD NSVYLPILNN SHVKNIIDYN ENNKLRLHNI 

        70         80         90        100        110        120 
VNFLYTVGQR WKNEEYSRRR TYIRDLKKYM GYSEAMAKLE ANWISMILCS KGGLYDVVEN 

       130        140        150        160        170        180 
ELGSRHIMDE WLPQDESYIK AFPKGKSIHL LAGNVPLSGI MSILRAILTK NQCIIKTSST 

       190        200        210        220        230        240 
DPFTANALAL SFIDVDPNHP ITRSLSVVYW PHQGDTSLAK EIMQHMDVIV AWGGEDAINW 

       250        260        270        280        290        300 
AVEHAPPYAD VIKFGSKKSF CIIDNPVDLT SAATGAAHDI CFYDQRACFS AQNIYYMGNQ 

       310        320        330        340        350        360 
YEEFKLALIE KLNLYAHILP NAKKDFDEKA AYSLVQKESL FAGLKVEVDV HQRWMIIESN 

       370        380        390        400        410        420 
AGVEFNQPLG RCVYLHHVDN IEQVLPYVQK NKTQTISIFP WESAFKYRDA LALRGAERIV 

       430        440        450        460        470        480 
EAGMNNIFRV GGSHDGMRPL QRLVTYISHE RPSHYTAKDV AVEIEQTRFL EEDKFLVFVP 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571866 Genomic DNA. Translation: CAE14372.1.
RefSeqNP_929340.1. NC_005126.1.

3D structure databases

ProteinModelPortalQ7N577.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu2079.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE14372; CAE14372; plu2079.
GeneID2802083.
KEGGplu:plu2079.
PATRIC20508221. VBIPhoLum48522_2348.

Organism-specific databases

GenoListplu2079.
CMRSearch...

Phylogenomic databases

eggNOGNOG15417.
HOGENOMHOG000005461.
KOK03400.
OMATVGQRWK.
OrthoDBEOG6WQD3S.
ProtClustDBCLSK923422.

Enzyme and pathway databases

UniPathwayUPA00569.

Family and domain databases

Gene3D3.40.605.10. 1 hit.
InterProIPR008670. Acyl-CoA_reduct_LuxC.
IPR016161. Ald_DH/histidinol_DH.
IPR016162. Ald_DH_N.
[Graphical view]
PfamPF05893. LuxC. 1 hit.
[Graphical view]
PIRSFPIRSF009414. LuxC. 1 hit.
SUPFAMSSF53720. SSF53720. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLUXC_PHOLL
AccessionPrimary (citable) accession number: Q7N577
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: November 13, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways