Reviewed, UniProtKB/Swiss-Prot Q7N577 (LUXC_PHOLL)

Names and origin

Protein names

Recommended name:
    Acyl-CoA reductase
    EC=1.2.1.50

Gene names

Name:	luxC
Ordered Locus Names:	plu2079

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase By similarity.
Catalytic activity	A long-chain aldehyde + CoA + NADP(+) = a long-chain acyl-CoA + NADPH.
Pathway	Lipid metabolism; bioluminescent fatty acid reduction.
Sequence similarities	Belongs to the luxC family.

Ontologies

Keywords
Biological process	Luminescence
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	bioluminescence Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	acyl-CoA reductase activity Inferred from electronic annotation. Source: InterPro long-chain-fatty-acyl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 480	480	Acyl-CoA reductase		PRO_0000220198

Sequences

	Sequence		Length	Mass (Da)
	Q7N577-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 48DC9106D75662BB	FASTA	480	54,815
	10 20 30 40 50 60 MTKKISFIIN GQVEIFPESD DLVQSINFGD NSVYLPILNN SHVKNIIDYN ENNKLRLHNI 70 80 90 100 110 120 VNFLYTVGQR WKNEEYSRRR TYIRDLKKYM GYSEAMAKLE ANWISMILCS KGGLYDVVEN 130 140 150 160 170 180 ELGSRHIMDE WLPQDESYIK AFPKGKSIHL LAGNVPLSGI MSILRAILTK NQCIIKTSST 190 200 210 220 230 240 DPFTANALAL SFIDVDPNHP ITRSLSVVYW PHQGDTSLAK EIMQHMDVIV AWGGEDAINW 250 260 270 280 290 300 AVEHAPPYAD VIKFGSKKSF CIIDNPVDLT SAATGAAHDI CFYDQRACFS AQNIYYMGNQ 310 320 330 340 350 360 YEEFKLALIE KLNLYAHILP NAKKDFDEKA AYSLVQKESL FAGLKVEVDV HQRWMIIESN 370 380 390 400 410 420 AGVEFNQPLG RCVYLHHVDN IEQVLPYVQK NKTQTISIFP WESAFKYRDA LALRGAERIV 430 440 450 460 470 480 EAGMNNIFRV GGSHDGMRPL QRLVTYISHE RPSHYTAKDV AVEIEQTRFL EEDKFLVFVP

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571866 Genomic DNA. Translation: CAE14372.1.
RefSeq	NP_929340.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2802083.
GenomeReviews	Gene locus plu2079 in contig BX470251_GR.
KEGG	plu:plu2079.
NMPDR	fig|243265.1.peg.1964.
Organism-specific databases
PhotoList	plu2079.
CMR	Search...
Phylogenomic databases
HOGENOM	Q7N577.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU2079-MON.
Family and domain databases
InterPro	IPR008670. LuxC. [Graphical view]
Pfam	PF05893. LuxC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LUXC_PHOLL

Accession

Primary (citable) accession number: Q7N577

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	December 15, 2003
Last modified:	November 25, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)