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Q7N577

- LUXC_PHOLL

UniProt

Q7N577 - LUXC_PHOLL

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Protein
Acyl-CoA reductase
Gene
luxC, plu2079
Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase By similarity.

Catalytic activityi

A long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.

Pathwayi

GO - Molecular functioni

  1. acyl-CoA dehydrogenase activity Source: InterPro
  2. long-chain-fatty-acyl-CoA reductase activity Source: UniProtKB-EC

GO - Biological processi

  1. bioluminescence Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Luminescence

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00569.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl-CoA reductase (EC:1.2.1.50)
Gene namesi
Name:luxC
Ordered Locus Names:plu2079
OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002514: Chromosome

Organism-specific databases

GenoListiplu2079.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 480480Acyl-CoA reductase
PRO_0000220198Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243265.plu2079.

Structurei

3D structure databases

ProteinModelPortaliQ7N577.

Family & Domainsi

Sequence similaritiesi

Belongs to the LuxC family.

Phylogenomic databases

eggNOGiNOG15417.
HOGENOMiHOG000005461.
KOiK03400.
OMAiGMNNIFR.
OrthoDBiEOG6WQD3S.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiIPR008670. Acyl-CoA_reduct_LuxC.
IPR016161. Ald_DH/histidinol_DH.
IPR016162. Ald_DH_N.
[Graphical view]
PfamiPF05893. LuxC. 1 hit.
[Graphical view]
PIRSFiPIRSF009414. LuxC. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7N577-1 [UniParc]FASTAAdd to Basket

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MTKKISFIIN GQVEIFPESD DLVQSINFGD NSVYLPILNN SHVKNIIDYN    50
ENNKLRLHNI VNFLYTVGQR WKNEEYSRRR TYIRDLKKYM GYSEAMAKLE 100
ANWISMILCS KGGLYDVVEN ELGSRHIMDE WLPQDESYIK AFPKGKSIHL 150
LAGNVPLSGI MSILRAILTK NQCIIKTSST DPFTANALAL SFIDVDPNHP 200
ITRSLSVVYW PHQGDTSLAK EIMQHMDVIV AWGGEDAINW AVEHAPPYAD 250
VIKFGSKKSF CIIDNPVDLT SAATGAAHDI CFYDQRACFS AQNIYYMGNQ 300
YEEFKLALIE KLNLYAHILP NAKKDFDEKA AYSLVQKESL FAGLKVEVDV 350
HQRWMIIESN AGVEFNQPLG RCVYLHHVDN IEQVLPYVQK NKTQTISIFP 400
WESAFKYRDA LALRGAERIV EAGMNNIFRV GGSHDGMRPL QRLVTYISHE 450
RPSHYTAKDV AVEIEQTRFL EEDKFLVFVP 480
Length:480
Mass (Da):54,815
Last modified:December 15, 2003 - v1
Checksum:i48DC9106D75662BB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571866 Genomic DNA. Translation: CAE14372.1.
RefSeqiNP_929340.1. NC_005126.1.
WP_011146334.1. NC_005126.1.

Genome annotation databases

EnsemblBacteriaiCAE14372; CAE14372; plu2079.
GeneIDi2802083.
KEGGiplu:plu2079.
PATRICi20508221. VBIPhoLum48522_2348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571866 Genomic DNA. Translation: CAE14372.1 .
RefSeqi NP_929340.1. NC_005126.1.
WP_011146334.1. NC_005126.1.

3D structure databases

ProteinModelPortali Q7N577.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243265.plu2079.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE14372 ; CAE14372 ; plu2079 .
GeneIDi 2802083.
KEGGi plu:plu2079.
PATRICi 20508221. VBIPhoLum48522_2348.

Organism-specific databases

GenoListi plu2079.

Phylogenomic databases

eggNOGi NOG15417.
HOGENOMi HOG000005461.
KOi K03400.
OMAi GMNNIFR.
OrthoDBi EOG6WQD3S.

Enzyme and pathway databases

UniPathwayi UPA00569 .

Family and domain databases

Gene3Di 3.40.605.10. 1 hit.
InterProi IPR008670. Acyl-CoA_reduct_LuxC.
IPR016161. Ald_DH/histidinol_DH.
IPR016162. Ald_DH_N.
[Graphical view ]
Pfami PF05893. LuxC. 1 hit.
[Graphical view ]
PIRSFi PIRSF009414. LuxC. 1 hit.
SUPFAMi SSF53720. SSF53720. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TT01.

Entry informationi

Entry nameiLUXC_PHOLL
AccessioniPrimary (citable) accession number: Q7N577
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: September 3, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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