Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q7N4V9 (HCAF_PHOLL)

Last modified November 3, 2009. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    3-phenylpropionate/cinnamic acid dioxygenase subunit beta
    EC=1.14.12.19
Alternative name(s):
    Digoxigenin subunit beta
Gene names
Name: hcaF
Ordered Locus Names: plu2205
OrganismPhotorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]
Taxonomic identifier141679 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length180 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively By similarity.

Catalytic activity

3-phenylpropanoic acid + NADH + O2 = cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+. HAMAP MF_01649

Cinnamic acid + H+ + NADH + O2 = cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+. HAMAP MF_01649

Pathway

Aromatic compound metabolism; 3-phenylpropanoate degradation. HAMAP MF_01649

Subunit structure

This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD) By similarity.

Sequence similarities

Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 1801803-phenylpropionate/cinnamic acid dioxygenase subunit beta HAMAP MF_01649
PRO_0000333713

Sequences

Sequence LengthMass (Da)Tools
Q7N4V9-1 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 3F29E545C70C1065

FASTA18021,783
        10         20         30         40         50         60 
MKELIVNQEK RVSPELHYEI SQFLYYEIAL LDEWRFRDWL ELLSEDLSYT MRTIVNAQTR 

        70         80         90        100        110        120 
DRRKSIQPPT TWLFNDNKFQ LERRIARLET GMAWAEEPPS RTRHLLTNLV ITETDLPDQF 

       130        140        150        160        170        180 
HVQSNYLLYR SQKERDEVFY VGKRLDCVRR NPKTDSWLIC KREITLDQAV LTFHNLSVLF 

« Hide

Cross-references

Sequence databases

BX571866 Genomic DNA. Translation: CAE14498.1.
RefSeqNP_929463.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2802210.
GenomeReviewsGene locus plu2205 in contig BX470251_GR.
KEGGplu:plu2205.
NMPDRfig|243265.1.peg.2087.

Organism-specific databases

PhotoListplu2205.
CMRSearch...

Phylogenomic databases

HOGENOMQ7N4V9.
OMAARRTICV.

Enzyme and pathway databases

BioCycPLUM243265:PLU2205-MON.

Family and domain databases

HAMAPMF_01649.
[Tree]
InterProIPR000391. Rng_hydr_dOase-bsu.
[Graphical view]
PfamPF00866. Ring_hydroxyl_B. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHCAF_PHOLL
AccessionPrimary (citable) accession number: Q7N4V9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 15, 2003
Last modified: November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents