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Protein

Xylose isomerase

Gene

xylA

Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciPLUM243265:G1GTE-2324-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:plu2275
OrganismiPhotorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaePhotorhabdus
Proteomesi
  • UP000002514 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957851 – 439Xylose isomeraseAdd BLAST439

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi243265.plu2275

Structurei

3D structure databases

ProteinModelPortaliQ7N4P7
SMRiQ7N4P7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q7N4P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRYFERVNR ISYEGRQSNN PLAFRHYNPE EIILGKKMKD HLRFAVCYWH
60 70 80 90 100
NFCWDGTDMF GSGAFERFWQ KGGDALELAK LKADVAFEFF YKLNIPFYCF
110 120 130 140 150
HDIDVAPEGC SLKEYIYNLG VMSDILADKQ AETGVKLLWG TANCFTHPRY
160 170 180 190 200
AAGASTNPDL NIFAYASAQV CQVMQMTKKL GGENYVLWGG REGYESLLNT
210 220 230 240 250
DLRQEREQIG RFMQMVVDYK YKIGFQGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE NEIKVNIEAN HATLAGHSFQ HEVATAIALG ILGSIDANRG
310 320 330 340 350
DAQLGWDTDQ FPNSVEENSL VMYEILKAGG FTTGGLNFDA KVRRQSIDID
360 370 380 390 400
DLFYGHIGAI DTMALSLKSA VKILVDGKLD EYVAQRYSGW NSELGRDILE
410 420 430
GKMTLDEVAH YAETLVQEPK HRSGQQELLE NLINRYIYD
Length:439
Mass (Da):49,984
Last modified:December 15, 2003 - v1
Checksum:iC850623FD48E4BE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571866 Genomic DNA Translation: CAE14568.1
RefSeqiWP_011146524.1, NC_005126.1

Genome annotation databases

EnsemblBacteriaiCAE14568; CAE14568; plu2275
KEGGiplu:plu2275

Similar proteinsi

Entry informationi

Entry nameiXYLA_PHOLL
AccessioniPrimary (citable) accession number: Q7N4P7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: December 15, 2003
Last modified: April 25, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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