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Q7N4P7 (XYLA_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase

EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:plu2275
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length439 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylopyranose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 439439Xylose isomerase HAMAP-Rule MF_00455
PRO_0000195785

Sites

Active site1011 By similarity
Active site1041 By similarity
Metal binding2321Magnesium 1 By similarity
Metal binding2681Magnesium 1 By similarity
Metal binding2681Magnesium 2 By similarity
Metal binding2711Magnesium 2 By similarity
Metal binding2961Magnesium 1 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3091Magnesium 2 By similarity
Metal binding3391Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7N4P7 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: C850623FD48E4BE5

FASTA43949,984
        10         20         30         40         50         60 
MHRYFERVNR ISYEGRQSNN PLAFRHYNPE EIILGKKMKD HLRFAVCYWH NFCWDGTDMF 

        70         80         90        100        110        120 
GSGAFERFWQ KGGDALELAK LKADVAFEFF YKLNIPFYCF HDIDVAPEGC SLKEYIYNLG 

       130        140        150        160        170        180 
VMSDILADKQ AETGVKLLWG TANCFTHPRY AAGASTNPDL NIFAYASAQV CQVMQMTKKL 

       190        200        210        220        230        240 
GGENYVLWGG REGYESLLNT DLRQEREQIG RFMQMVVDYK YKIGFQGTLL IEPKPQEPTK 

       250        260        270        280        290        300 
HQYDYDVATV YGFLKQFGLE NEIKVNIEAN HATLAGHSFQ HEVATAIALG ILGSIDANRG 

       310        320        330        340        350        360 
DAQLGWDTDQ FPNSVEENSL VMYEILKAGG FTTGGLNFDA KVRRQSIDID DLFYGHIGAI 

       370        380        390        400        410        420 
DTMALSLKSA VKILVDGKLD EYVAQRYSGW NSELGRDILE GKMTLDEVAH YAETLVQEPK 

       430 
HRSGQQELLE NLINRYIYD 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571866 Genomic DNA. Translation: CAE14568.1.
RefSeqNP_929532.1. NC_005126.1.

3D structure databases

ProteinModelPortalQ7N4P7.
SMRQ7N4P7. Positions 3-439.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu2275.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE14568; CAE14568; plu2275.
GeneID2802280.
KEGGplu:plu2275.
PATRIC20508691. VBIPhoLum48522_2584.

Organism-specific databases

GenoListplu2275.
CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMALFHAHIG.
OrthoDBEOG62NX4R.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. SSF51658. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_PHOLL
AccessionPrimary (citable) accession number: Q7N4P7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families