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Q7N3Q8 (ARND_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD

EC=3.5.1.n3
Gene names
Name:arnD
Ordered Locus Names:plu2657
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01870

Catalytic activity

4-deoxy-4-formamido-beta-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + H2O = 4-amino-4-deoxy-alpha-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + formate. HAMAP-Rule MF_01870

Pathway

Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2. HAMAP-Rule MF_01870

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP-Rule MF_01870

Sequence similarities

Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.

Contains 1 NodB homology domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD HAMAP-Rule MF_01870
PRO_0000383517

Regions

Domain2 – 261260NodB homology

Sequences

Sequence LengthMass (Da)Tools
Q7N3Q8 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 1EAE5892D18DDC1F

FASTA29733,475
        10         20         30         40         50         60 
MKQIGLRVDV DTYRGTVEGV PKLLKILAKH QIQASFFFSV GPDNMGRHLW RLLRPKFLWK 

        70         80         90        100        110        120 
MLRSNAASLY GLDILLAGTA WPGKKIAKDL GYLMKQTLNA GHEVGLHAWD HQRWQAKVGR 

       130        140        150        160        170        180 
WSEAQLTEQV KLGVDALVQA IGQRVTCSAV AGWRADERVL AVKQQFGFDY NSDCRGTHPF 

       190        200        210        220        230        240 
RPILPDGTLG TVQIPVTLPT YDEVIGIQVK DEDFNQFILD KMKNSQGVPV YTIHTEVEGM 

       250        260        270        280        290 
SKSTEFATLL EMVHQENIQF CALSHLLPEN IQRLPVGRIV RSEFPGREGW LGCQQEA 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571867 Genomic DNA. Translation: CAE15031.1.
RefSeqNP_929892.1. NC_005126.1.

3D structure databases

ProteinModelPortalQ7N3Q8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu2657.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE15031; CAE15031; plu2657.
GeneID2802665.
KEGGplu:plu2657.
PATRIC20509547. VBIPhoLum48522_3010.

Organism-specific databases

GenoListplu2657.
CMRSearch...

Phylogenomic databases

eggNOGCOG0726.
HOGENOMHOG000261199.
KOK13014.
OMALHAWDHF.
OrthoDBEOG6423D0.

Enzyme and pathway databases

UniPathwayUPA00030.
UPA00036; UER00496.

Family and domain databases

Gene3D3.20.20.370. 2 hits.
HAMAPMF_01870. ArnD.
InterProIPR023557. ArnD.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. Polysac_deacetylase.
[Graphical view]
PfamPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMSSF88713. SSF88713. 2 hits.
PROSITEPS51677. NODB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARND_PHOLL
AccessionPrimary (citable) accession number: Q7N3Q8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways