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Q7N3B7

- Q7N3B7_PHOLL

UniProt

Q7N3B7 - Q7N3B7_PHOLL

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:plu2801Imported
    OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)Imported
    Taxonomic identifieri243265 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
    ProteomesiUP000002514: Chromosome

    Organism-specific databases

    GenoListiplu2801.

    Interactioni

    Protein-protein interaction databases

    STRINGi243265.plu2801.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7N3B7.
    SMRiQ7N3B7. Positions 1-417.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7N3B7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESKVVIPAE GKKITVDAKG KLVVPNNPVI PYIEGDGIGV DVTPAMLKVV    50
    DAAVQKAYQG ERKISWMEIY TGEKSTHVYG KDVWLPDETL DLIREYRVAI 100
    KGPLTTPVGG GIRSLNVALR QQLDLYVCLR PVRYYQGTPS PVKQPELTDM 150
    VIFRENAEDI YAGIEWKAGS VEADKVIKFL QEEMGVNKIR FPQQCGIGVK 200
    PCSEEGTKRL VRAAIEYAID NDRESVTLVH KGNIMKFTEG AFKDWGYQLA 250
    REEFGGELLD GGPWVKIKNP KNGKEIIVKD VIADAFLQQI LLRPAEYDVI 300
    ACMNLNGDYI SDALAAQVGG IGIAPGANIG DECALFEATH GTAPKYAGQD 350
    KVNPGSVILS AEMMLRHMGW TEAADLIVKG MEGAIAAKTV TYDFERLMEG 400
    AKLLKCSEFG DAIIQHM 417
    Length:417
    Mass (Da):45,766
    Last modified:December 15, 2003 - v1
    Checksum:i0EFC80B0886E7DD1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571868 Genomic DNA. Translation: CAE15175.1.
    RefSeqiNP_930035.1. NC_005126.1.
    WP_011147021.1. NC_005126.1.

    Genome annotation databases

    EnsemblBacteriaiCAE15175; CAE15175; plu2801.
    GeneIDi2802809.
    KEGGiplu:plu2801.
    PATRICi20509891. VBIPhoLum48522_3185.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571868 Genomic DNA. Translation: CAE15175.1 .
    RefSeqi NP_930035.1. NC_005126.1.
    WP_011147021.1. NC_005126.1.

    3D structure databases

    ProteinModelPortali Q7N3B7.
    SMRi Q7N3B7. Positions 1-417.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243265.plu2801.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE15175 ; CAE15175 ; plu2801 .
    GeneIDi 2802809.
    KEGGi plu:plu2801.
    PATRICi 20509891. VBIPhoLum48522_3185.

    Organism-specific databases

    GenoListi plu2801.

    Phylogenomic databases

    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TT01Imported.

    Entry informationi

    Entry nameiQ7N3B7_PHOLL
    AccessioniPrimary (citable) accession number: Q7N3B7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3