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Q7N3B7 (Q7N3B7_PHOLL) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CAE15175.1
Ordered Locus Names:plu2801
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP] EMBL CAE15175.1
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus ›

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q7N3B7 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 0EFC80B0886E7DD1

FASTA41745,766
        10         20         30         40         50         60 
MESKVVIPAE GKKITVDAKG KLVVPNNPVI PYIEGDGIGV DVTPAMLKVV DAAVQKAYQG 

        70         80         90        100        110        120 
ERKISWMEIY TGEKSTHVYG KDVWLPDETL DLIREYRVAI KGPLTTPVGG GIRSLNVALR 

       130        140        150        160        170        180 
QQLDLYVCLR PVRYYQGTPS PVKQPELTDM VIFRENAEDI YAGIEWKAGS VEADKVIKFL 

       190        200        210        220        230        240 
QEEMGVNKIR FPQQCGIGVK PCSEEGTKRL VRAAIEYAID NDRESVTLVH KGNIMKFTEG 

       250        260        270        280        290        300 
AFKDWGYQLA REEFGGELLD GGPWVKIKNP KNGKEIIVKD VIADAFLQQI LLRPAEYDVI 

       310        320        330        340        350        360 
ACMNLNGDYI SDALAAQVGG IGIAPGANIG DECALFEATH GTAPKYAGQD KVNPGSVILS 

       370        380        390        400        410 
AEMMLRHMGW TEAADLIVKG MEGAIAAKTV TYDFERLMEG AKLLKCSEFG DAIIQHM

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References

[1]"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens."
Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. expand/collapse author list , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F.
Nat. Biotechnol. 21:1307-1313(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TT01.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX571868 Genomic DNA. Translation: CAE15175.1.
RefSeqNP_930035.1. NC_005126.1.

3D structure databases

HSSPHSSP built from PDB template 1PB3 based on UniProtKB P08200.
ProteinModelPortalQ7N3B7.
SMRQ7N3B7. Positions 1-417.
ModBaseSearch...

Protein-protein interaction databases

STRING243265.plu2801.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE15175; CAE15175; plu2801.
GeneID2802809.
KEGGplu:plu2801.
PATRIC20509891. VBIPhoLum48522_3185.

Organism-specific databases

GenoListplu2801.
CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
ProtClustDBPRK07006.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7N3B7_PHOLL
AccessionPrimary (citable) accession number: Q7N3B7
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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