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Q7N3B7

- Q7N3B7_PHOLL

UniProt

Q7N3B7 - Q7N3B7_PHOLL

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Protein

Isocitrate dehydrogenase [NADP]

Gene
icd, plu2801
Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:plu2801Imported
OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)Imported
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002514: Chromosome

Organism-specific databases

GenoListiplu2801.

Interactioni

Protein-protein interaction databases

STRINGi243265.plu2801.

Structurei

3D structure databases

ProteinModelPortaliQ7N3B7.
SMRiQ7N3B7. Positions 1-417.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7N3B7-1 [UniParc]FASTAAdd to Basket

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MESKVVIPAE GKKITVDAKG KLVVPNNPVI PYIEGDGIGV DVTPAMLKVV    50
DAAVQKAYQG ERKISWMEIY TGEKSTHVYG KDVWLPDETL DLIREYRVAI 100
KGPLTTPVGG GIRSLNVALR QQLDLYVCLR PVRYYQGTPS PVKQPELTDM 150
VIFRENAEDI YAGIEWKAGS VEADKVIKFL QEEMGVNKIR FPQQCGIGVK 200
PCSEEGTKRL VRAAIEYAID NDRESVTLVH KGNIMKFTEG AFKDWGYQLA 250
REEFGGELLD GGPWVKIKNP KNGKEIIVKD VIADAFLQQI LLRPAEYDVI 300
ACMNLNGDYI SDALAAQVGG IGIAPGANIG DECALFEATH GTAPKYAGQD 350
KVNPGSVILS AEMMLRHMGW TEAADLIVKG MEGAIAAKTV TYDFERLMEG 400
AKLLKCSEFG DAIIQHM 417
Length:417
Mass (Da):45,766
Last modified:December 15, 2003 - v1
Checksum:i0EFC80B0886E7DD1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571868 Genomic DNA. Translation: CAE15175.1.
RefSeqiNP_930035.1. NC_005126.1.
WP_011147021.1. NC_005126.1.

Genome annotation databases

EnsemblBacteriaiCAE15175; CAE15175; plu2801.
GeneIDi2802809.
KEGGiplu:plu2801.
PATRICi20509891. VBIPhoLum48522_3185.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571868 Genomic DNA. Translation: CAE15175.1 .
RefSeqi NP_930035.1. NC_005126.1.
WP_011147021.1. NC_005126.1.

3D structure databases

ProteinModelPortali Q7N3B7.
SMRi Q7N3B7. Positions 1-417.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243265.plu2801.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE15175 ; CAE15175 ; plu2801 .
GeneIDi 2802809.
KEGGi plu:plu2801.
PATRICi 20509891. VBIPhoLum48522_3185.

Organism-specific databases

GenoListi plu2801.

Phylogenomic databases

HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TT01.

Entry informationi

Entry nameiQ7N3B7_PHOLL
AccessioniPrimary (citable) accession number: Q7N3B7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: September 3, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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