Reviewed, UniProtKB/Swiss-Prot Q7N397 (NAGZ_PHOLL)

Names and origin

Protein names

Recommended name:
    Beta-hexosaminidase
    EC=3.2.1.52
Alternative name(s):
    N-acetyl-beta-glucosaminidase
    Beta-N-acetylhexosaminidase

Gene names

Name:	nagZ
Ordered Locus Names:	plu2822

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity.
Catalytic activity	Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP MF_00364
Pathway	Cell wall biogenesis; peptidoglycan recycling. HAMAP MF_00364
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.

Ontologies

Keywords
Biological process	Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Cytoplasm
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan turnover Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	beta-N-acetylhexosaminidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Beta-hexosaminidase HAMAP MF_00364		PRO_0000210794
Sites
	Active site	248	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7N397-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 0150EE572B011C65	FASTA	340	38,018
	10 20 30 40 50 60 MGPVMLDVVG YELDNEEKEI LQHPLVGGLI LFTRNFYDVE QLRELVRQIR KASRHRLVIA 70 80 90 100 110 120 VDQEGGRVQR FREGFTCLPA AQSFAGLSDN LNGTQLAEEA GWLMASEMIA MDIDISFAPV 130 140 150 160 170 180 LDLGHQCAAI GERSFHEDPE QAKMMAEHFI KGMHSAGMKS TGKHFPGHGA VNADSHKETP 190 200 210 220 230 240 CDDRPLEVIC HHDMSIFRDF IQRNLLDAIM PAHVIYPQVD KHPASGSSYW LKSVLRQQLG 250 260 270 280 290 300 FNGVIFSDDL SMEGAAMMGS YVERGQTALN AGCDMILICN NRDGAVSALD NLPLTKVEKL 310 320 330 340 SELYHRGGQY SLNELKNSER WQQANKALTA LYEQWQDCAR

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571868 Genomic DNA. Translation: CAE15196.1.
RefSeq	NP_930056.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2802830.
GenomeReviews	Gene locus plu2822 in contig BX470251_GR.
KEGG	plu:plu2822.
NMPDR	fig|243265.1.peg.2680.
Organism-specific databases
PhotoList	plu2822.
CMR	Search...
Phylogenomic databases
HOGENOM	Q7N397.
OMA	WQYMANT.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU2822-MON.
BRENDA	3.2.1.52. 308689.
Family and domain databases
HAMAP	MF_00364. [Tree]
InterPro	IPR019800. Glyco_hydro_3_AS. IPR001764. Glyco_hydro_3_N. [Graphical view]
Gene3D	G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
Pfam	PF00933. Glyco_hydro_3. 1 hit. [Graphical view]
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NAGZ_PHOLL

Accession

Primary (citable) accession number: Q7N397

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)