Q7N2G8 (ASTA_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine N-succinyltransferase
Short name=AST
EC=2.3.1.109

Alternative name(s):
AOST

Gene names

Name:	astA
Ordered Locus Names:	plu3109

Organism

Photorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]

Taxonomic identifier

243265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine By similarity. HAMAP MF_01171
Catalytic activity	Succinyl-CoA + L-arginine = CoA + N(2)-succinyl-L-arginine. HAMAP MF_01171
Pathway	Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. HAMAP MF_01171
Sequence similarities	Belongs to the arginine N-succinyltransferase family.

Ontologies

Keywords
Biological process	Arginine metabolism
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine N-succinyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Arginine N-succinyltransferase HAMAP MF_01171		PRO_0000262326
Sites
	Active site	229	1	Proton donor Potential
	Binding site	125	1	Succinyl-CoA; via amide nitrogen Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7N2G8 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: CB13861B865CFA62	FASTA	343	37,995
	10 20 30 40 50 60 MMLFRAVRHS DLNGVQSLSQ RAGIGLTSFP NNLDQLRSRI ARSVDTFDGK LARAQQGFLF 70 80 90 100 110 120 VLEDTSANRV AGVSAIEVAV GLEEPFYNFR VQKTIRSSRE LGIYKSIEAL TLEQDQTGNS 130 140 150 160 170 180 ELCTLFLDPE YQKGRNGTFL SKARFLFIAA FRDIFSKTIF AEMRGVADEQ GNSPFWNSLG 190 200 210 220 230 240 QHFFGIPFSQ ADYLTGIGSK TFIAELMPLH PIYISLLSAE AQKVIGQVHE KTVPARAILE 250 260 270 280 290 300 KEGLIYQGHI DIFDGGALLQ AEIDRIRAVK ESRLVSVSKA ESVTRDDGVP CIVANQQFSE 310 320 330 340 FRALLLNVVC DSNELFLTAA EMGALQVSDG DQVRLVSLFP KEN

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571869 Genomic DNA. Translation: CAE15483.1.
RefSeq	NP_930341.1. NC_005126.1.
3D structure databases
HSSP	HSSP built from PDB template 1YLE based on UniProtKB P80357.
ProteinModelPortal	Q7N2G8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2803120.
GenomeReviews	Gene locus plu3109 in contig BX470251_GR.
KEGG	plu:plu3109.
NMPDR	fig|243265.1.peg.2965.
PATRIC	20510578. VBIPhoLum48522_3528.
Organism-specific databases
GenoList	plu3109.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG377601.
OMA	MAEHPHR.
PhylomeDB	Q7N2G8.
ProtClustDB	CLSK2760685.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU3109-MONOMER.
Family and domain databases
HAMAP	MF_01171. AstA. [Tree]
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR007041. Arg_N-succinylTrfase_Ast/AOST. IPR017650. Arginine_N-succinylTrfase_AstA. [Graphical view]
KO	K00673.
Pfam	PF04958. AstA. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR03243. Arg_catab_AOST. 1 hit. TIGR03244. Arg_catab_AstA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ASTA_PHOLL

Accession

Primary (citable) accession number: Q7N2G8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program