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Q7N1U6 (PPNK_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase

Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:plu3373
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000229665

Sequences

Sequence LengthMass (Da)Tools
Q7N1U6 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: D4A3A4593BBD73AE

FASTA29232,432
        10         20         30         40         50         60 
MNKKFKCIGI VGHPRHPEAL ATHEMLYHWL KSKGYSVIID RQVAKDIGLK DAQTGGLTEI 

        70         80         90        100        110        120 
GKQADLAVVV GGDGNMLGAA RVLSRYDIKV IGINRGNLGF LTDLDPDNAL QQLSEVLDGE 

       130        140        150        160        170        180 
YRNEHRFLLE AQVRRNGQKP RISTAINEVV LHPGKVAHMI EFEVYIDERF AFSQRSDGLI 

       190        200        210        220        230        240 
IATPTGSTAY SLSAGGPILT PNLDAIVLVP MFPHTLSSRP LVISSESSIR LKFSQNSNDY 

       250        260        270        280        290 
EVSCDSQIVL PIQDGEDVII SRSKQKLNLI HPQDYNYFNT LSTKLSWSKK MF 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571870 Genomic DNA. Translation: CAE15747.1.
RefSeqNP_930591.1. NC_005126.1.

3D structure databases

ProteinModelPortalQ7N1U6.
SMRQ7N1U6. Positions 5-292.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu3373.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE15747; CAE15747; plu3373.
GeneID2803385.
KEGGplu:plu3373.
PATRIC20511208. VBIPhoLum48522_3846.

Organism-specific databases

GenoListplu3373.
CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000227221.
KOK00858.
OMAGMVELRV.
OrthoDBEOG6PZXDR.
ProtClustDBPRK03378.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_PHOLL
AccessionPrimary (citable) accession number: Q7N1U6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families