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Protein

Agmatinase

Gene

speB

Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of putrescine from agmatine.UniRule annotation

Catalytic activityi

Agmatine + H2O = putrescine + urea.UniRule annotation

Cofactori

Mn2+UniRule annotation

Pathwayi: putrescine biosynthesis via agmatine pathway

This protein is involved in step 1 of the subpathway that synthesizes putrescine from agmatine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Agmatinase (speB)
This subpathway is part of the pathway putrescine biosynthesis via agmatine pathway, which is itself part of Amine and polyamine biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes putrescine from agmatine, the pathway putrescine biosynthesis via agmatine pathway and in Amine and polyamine biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi128ManganeseUniRule annotation1
Metal bindingi151ManganeseUniRule annotation1
Metal bindingi153ManganeseUniRule annotation1
Metal bindingi155ManganeseUniRule annotation1
Metal bindingi232ManganeseUniRule annotation1
Metal bindingi234ManganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processPolyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyciPLUM243265:G1GTE-3732-MONOMER
UniPathwayiUPA00534; UER00287

Names & Taxonomyi

Protein namesi
Recommended name:
AgmatinaseUniRule annotation (EC:3.5.3.11UniRule annotation)
Alternative name(s):
Agmatine ureohydrolaseUniRule annotation
Short name:
AUHUniRule annotation
Gene namesi
Name:speBUniRule annotation
Ordered Locus Names:plu3680
OrganismiPhotorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Taxonomic identifieri243265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaePhotorhabdus
Proteomesi
  • UP000002514 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001737371 – 307AgmatinaseAdd BLAST307

Interactioni

Protein-protein interaction databases

STRINGi243265.plu3680

Structurei

3D structure databases

ProteinModelPortaliQ7N122
SMRiQ7N122
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family. Agmatinase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYW Bacteria
COG0010 LUCA
HOGENOMiHOG000204320
KOiK01480
OMAiDTYFGAE
OrthoDBiPOG091H0384

Family and domain databases

HAMAPiMF_01418 SpeB, 1 hit
InterProiView protein in InterPro
IPR023694 Agmatinase
IPR005925 Agmatinase-rel
IPR006035 Ureohydrolase
IPR023696 Ureohydrolase_dom_sf
IPR020855 Ureohydrolase_Mn_BS
PfamiView protein in Pfam
PF00491 Arginase, 1 hit
PIRSFiPIRSF036979 Arginase, 1 hit
SUPFAMiSSF52768 SSF52768, 1 hit
TIGRFAMsiTIGR01230 agmatinase, 1 hit
PROSITEiView protein in PROSITE
PS01053 ARGINASE_1, 1 hit
PS51409 ARGINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7N122-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTISTLGNQQ DDSLVSNAFG FLRFPLNFQP YSSDAEWVIT GVPFDMATSG
60 70 80 90 100
RAGSRHGPAA IRQVSTNLAW ESRRWPWDFK LHNCLKVVDC GDVVFNFGDA
110 120 130 140 150
QDMSDKLQAH AEKVLASGKR MLSFGGDHFI TLPLLRAHAK HFGKMALVHF
160 170 180 190 200
DAHADTYPNG SQFDHGTMFY HAPNEGLIDP HHSVQIGIRT EHGRDNGFTV
210 220 230 240 250
LDADQVNDRS VDDLLAQIKE TVGDMPVYLT FDIDCLDPAF APGTGTPVIG
260 270 280 290 300
GLTTDRALKL LRGLQPLNIV GMDVVEVAPA YDQSEITALA GATIALEMLY

LQASKKR
Length:307
Mass (Da):33,668
Last modified:December 15, 2003 - v1
Checksum:i63B97DC9382A63C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571871 Genomic DNA Translation: CAE16053.1
RefSeqiWP_011147843.1, NC_005126.1

Genome annotation databases

EnsemblBacteriaiCAE16053; CAE16053; plu3680
KEGGiplu:plu3680

Similar proteinsi

Entry informationi

Entry nameiSPEB_PHOLL
AccessioniPrimary (citable) accession number: Q7N122
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: December 15, 2003
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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