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Q7N121

- SPEA_PHOLL

UniProt

Q7N121 - SPEA_PHOLL

Protein

Biosynthetic arginine decarboxylase

Gene

speA

Organism
Photorhabdus luminescens subsp. laumondii (strain TT01)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalyzes the biosynthesis of agmatine from arginine.UniRule annotation

    Catalytic activityi

    L-arginine = agmatine + CO2.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation
    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. arginine decarboxylase activity Source: UniProtKB-HAMAP
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. arginine catabolic process Source: InterPro
    2. putrescine biosynthetic process Source: UniProtKB-HAMAP
    3. spermidine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Polyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Magnesium, Metal-binding, Pyridoxal phosphate

    Enzyme and pathway databases

    UniPathwayiUPA00186; UER00284.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Biosynthetic arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
    Short name:
    ADCUniRule annotation
    Gene namesi
    Name:speAUniRule annotation
    Ordered Locus Names:plu3681
    OrganismiPhotorhabdus luminescens subsp. laumondii (strain TT01)
    Taxonomic identifieri243265 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
    ProteomesiUP000002514: Chromosome

    Organism-specific databases

    GenoListiplu3681.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 634634Biosynthetic arginine decarboxylasePRO_0000149967Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei103 – 1031N6-(pyridoxal phosphate)lysineUniRule annotation

    Proteomic databases

    PRIDEiQ7N121.

    Interactioni

    Protein-protein interaction databases

    STRINGi243265.plu3681.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7N121.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni283 – 29311Substrate-bindingUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1166.
    HOGENOMiHOG000029191.
    KOiK01585.
    OMAiIDHYVDG.
    OrthoDBiEOG676Z0R.

    Family and domain databases

    Gene3Di2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPiMF_01417. SpeA.
    InterProiIPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSiPR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR01273. speA. 1 hit.
    PROSITEiPS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7N121-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNDNIARKMQ QTYNIAYWGG SYYYVNDLGN VSVCPNPDLP GAKIDLAELV    50
    KRVQQEQKHL RLPALFCFPQ ILQHRLRSIN AAFKRARESY GYKGDYFLVY 100
    PIKVNQQRRV IESLASSGEP LGLEAGSKAE LMAVLAHAGM TRTVIVCNGY 150
    KDREYIRLAL IGEKLGHKVY LVIEKMSEIA QVLEEAERLN VIPRLGVRAR 200
    LASQGSGKWQ ASGGEKSKFG LAATQVLQLV ETLRAVDRLD SLQLLHFHLG 250
    SQLANIRDIA TGVRESARFY VELHKLGVNI QCFDVGGGLG VDYEGTRSQS 300
    DCSVNYGLNE YANNVIWGIG DACDEHGLPH PTVITESGRA LTAHHTVLVS 350
    NVIGVERNEF TQTTPPAEDA SRPLTSLWET WQEMHSEGNR RSLRESLHDG 400
    QLDLHDVHTQ YAHGMLDLTE RAWAEELYLN ICRRIQQDLD PSNRAHRPII 450
    DELQERMADK FYVNFSLFQS LPDAWGIDQL FPVLPIEGLD KPLDRRAVLL 500
    DITCDSDGIV DHYVDGDGVA ATMPMPAYDP DCPPMIGFFM VGAYQEILGN 550
    MHNLFGDTAA IDVYVFDNGE VTYNQSEEGD SVADMLQYVK LDPNVLMARF 600
    RDQVKGADLD TGLQEQFLLE FESGLYGYTY LEDE 634
    Length:634
    Mass (Da):71,155
    Last modified:December 15, 2003 - v1
    Checksum:iA3268D93070FDCB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571871 Genomic DNA. Translation: CAE16054.1.
    RefSeqiNP_930889.1. NC_005126.1.

    Genome annotation databases

    EnsemblBacteriaiCAE16054; CAE16054; plu3681.
    GeneIDi2803693.
    KEGGiplu:plu3681.
    PATRICi20511872. VBIPhoLum48522_4177.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571871 Genomic DNA. Translation: CAE16054.1 .
    RefSeqi NP_930889.1. NC_005126.1.

    3D structure databases

    ProteinModelPortali Q7N121.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243265.plu3681.

    Proteomic databases

    PRIDEi Q7N121.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE16054 ; CAE16054 ; plu3681 .
    GeneIDi 2803693.
    KEGGi plu:plu3681.
    PATRICi 20511872. VBIPhoLum48522_4177.

    Organism-specific databases

    GenoListi plu3681.

    Phylogenomic databases

    eggNOGi COG1166.
    HOGENOMi HOG000029191.
    KOi K01585.
    OMAi IDHYVDG.
    OrthoDBi EOG676Z0R.

    Enzyme and pathway databases

    UniPathwayi UPA00186 ; UER00284 .

    Family and domain databases

    Gene3Di 2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPi MF_01417. SpeA.
    InterProi IPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSi PR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR01273. speA. 1 hit.
    PROSITEi PS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TT01.

    Entry informationi

    Entry nameiSPEA_PHOLL
    AccessioniPrimary (citable) accession number: Q7N121
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2004
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3