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Q7N0B9 (UPPP_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:plu3973
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151175

Regions

Transmembrane22 – 4221Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane92 – 11221Helical; Potential
Transmembrane118 – 13821Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane228 – 24821Helical; Potential
Transmembrane251 – 27121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q7N0B9 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: B64DFAB3419B8198

FASTA27229,619
        10         20         30         40         50         60 
MTDLSTLFHA AILGVVEGLT EFLPVSSTGH MIIVGHMLGF TGDKAETFEV IIQLGSILAV 

        70         80         90        100        110        120 
VVVFWRRLFG LIGIHFGEVP HEGKTNGKLK LSHIILAMLP AVTLGLMFHD VIKSLFNPQS 

       130        140        150        160        170        180 
VMYALVIGGV LLITAEILKP KTPKAEGLDD ITYRQAFMIG CFQCLALWPG FSRSGATISG 

       190        200        210        220        230        240 
GMLMGVNRYT ASEFSFILAV PMMMGASGLD LYKSLHFLSA SDIPMFAVGF VTAFVVALVA 

       250        260        270 
IKTFLALIKR ISFIPFAIYR FIVAAAVYWV FM 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571872 Genomic DNA. Translation: CAE16345.1.
RefSeqNP_931173.1. NC_005126.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243265.plu3973.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE16345; CAE16345; plu3973.
GeneID2803984.
KEGGplu:plu3973.
PATRIC20512510. VBIPhoLum48522_4498.

Organism-specific databases

GenoListplu3973.
CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PHOLL
AccessionPrimary (citable) accession number: Q7N0B9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families