Reviewed, UniProtKB/Swiss-Prot Q7MZY6 (SYK3_PHOLL)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Synonyms:	genX
Ordered Locus Names:	plu4121

Organism

Photorhabdus luminescens subsp. laumondii [Complete proteome] [HAMAP]

Taxonomic identifier

141679 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 325	325	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_0000152726

Sequences

	Sequence		Length	Mass (Da)
	Q7MZY6-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 74BD358E10F54A61	FASTA	325	36,754
	10 20 30 40 50 60 MSETANWQPS AAIANLLKRA TILAEIRRFF ADRGVLEVET PAMGQFTVTD IQLFSFQTEF 70 80 90 100 110 120 VGPGAADGMT LYLMTSPEYH MKRLLAAGSG PIYQLGRCFR NEEAGRYHNP EFTMLEWYRP 130 140 150 160 170 180 HYDMYRLMNE VDDLLQQILD CESAESLSYQ QAFLRYLDID PLSAEKEKLR EIAAKLDLSN 190 200 210 220 230 240 IADIEEDRDT LLQLLFAVGV EPHIGTEKPT FIYHFPASQA SLAEISKEDH RVAERFEVYF 250 260 270 280 290 300 KGVELANGFR ELTDSHEQCQ RFERDNRKRA ALGLPVRPID ENLIGALKQG MPECAGVALG 310 320 VDRLVMLALG AEKLSDVMAF SITKA

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571872 Genomic DNA. Translation: CAE16493.1.
RefSeq	NP_931311.1.
3D structure databases
SMR	Q7MZY6. Positions 13-324.
ModBase	Search...
Genome annotation databases
GeneID	2804133.
KEGG	plu:plu4121.
NMPDR	fig|243265.1.peg.3934.
Organism-specific databases
PhotoList	plu4121.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG631383.
OMA	PGNEAHL.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU4121-MONOMER.
BRENDA	6.1.1.6. 308689.
Family and domain databases
HAMAP	MF_00174. Put_Lys_tRNA_synth. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-dom. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_PHOLL

Accession

Primary (citable) accession number: Q7MZY6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)