Q7MZN0 (RSMC_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172

Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC

Gene names

Name:	rsmC
Ordered Locus Names:	plu4252

Organism

Photorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]

Taxonomic identifier

243265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862
Catalytic activity	S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862
Subunit structure	Monomer By similarity. HAMAP MF_01862
Subcellular location	Cytoplasm Potential HAMAP MF_01862.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 338	338	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000369730

Sequences

	Sequence		Length	Mass (Da)
	Q7MZN0 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: F9B9410776D75232	FASTA	338	37,646
	10 20 30 40 50 60 MSALTPASEV ILRHREQFSS HHLLFAGDIQ DTLATQIDAA SVRVHTNQYH HWQSLIRTLG 70 80 90 100 110 120 ESAWFGLVAE KAFTQGCDTL IYYWPKSKQE ARFQLRSLFS VLPKGINIFI VGENRSGVRS 130 140 150 160 170 180 VDKLMDGMAT FRKIDSARRC SLFYGQLEHE VQFEQDNWWN SYQVENVIVN TLPGVFSQDE 190 200 210 220 230 240 LDVGSRLLLS TFDKPLSGNL LDIACGAGVL AAVLGKKNPE LALTLSDVNA AAIASSKATL 250 260 270 280 290 300 KANKLEGHVV VSNVYSNIED KFDWIISNPP FHEGLKTSLL ATDDLIRQAP NHLKPGGKLR 310 320 330 IVANAFLPYP DLLDKTFGTH EVIAQTGKFK VYQATKKF

References

[1]

"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens." Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K. , Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F. Nat. Biotechnol. 21:1307-1313(2003) [PubMed: 14528314] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TT01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571873 Genomic DNA. Translation: CAE16624.1.
RefSeq	NP_931429.1. NC_005126.1.
3D structure databases
ProteinModelPortal	Q7MZN0.
SMR	Q7MZN0. Positions 3-335.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2804265.
GenomeReviews	Gene locus plu4252 in contig BX470251_GR.
KEGG	plu:plu4252.
NMPDR	fig|243265.1.peg.4052.
PATRIC	20513134. VBIPhoLum48522_4810.
Organism-specific databases
GenoList	plu4252.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG296757.
OMA	TGKFKVY.
PhylomeDB	Q7MZN0.
ProtClustDB	PRK09489.
Enzyme and pathway databases
BioCyc	PLUM243265:PLU4252-MONOMER.
Family and domain databases
HAMAP	MF_01862. 16SrRNA_methyltr_C. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR013675. Mtase_sm_N. IPR023543. rRNA_ssu_MeTfrase_C. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_PHOLL

Accession

Primary (citable) accession number: Q7MZN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program