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Q7MZB5 (UBIC_PHOLL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate--pyruvate lyase
Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:plu4378
OrganismPhotorhabdus luminescens subsp. laumondii (strain TT01) [Complete proteome] [HAMAP]
Taxonomic identifier243265 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Photorhabdus

Protein attributes

Sequence length168 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subunit structure

Monomer By similarity. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Sequence caution

The sequence CAE16750.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 168168Chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000240553

Sites

Binding site361Substrate; via amide nitrogen By similarity
Binding site781Substrate By similarity
Binding site1161Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MZB5 [UniParc].

Last modified June 26, 2007. Version 2.
Checksum: 369283910318DE3D

FASTA16819,412
        10         20         30         40         50         60 
MSTDSILTTV PIQWLSVDSP VLPDEVLDWL MELGSMTRRF EQYCNSVRII PFRECFITEE 

        70         80         90        100        110        120 
QLSDENERLL TGQRYWLREI VLCGDNIPWL LGRTLIPETT LTGPDESLVD LGTVPLGRYL 

       130        140        150        160 
FSGNKLTRDY IHVGQQGNRW ARRSLLRLSG KPLLLTEVFL PESPVYKR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX571873 Genomic DNA. Translation: CAE16750.1. Different initiation.
RefSeqNP_931551.2. NC_005126.1.

3D structure databases

ProteinModelPortalQ7MZB5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2804394.
GenomeReviewsGene locus plu4378 in contig BX470251_GR.
KEGGplu:plu4378.
NMPDRfig|243265.1.peg.4174.
PATRIC20513438. VBIPhoLum48522_4960.

Organism-specific databases

GenoListplu4378.
CMRSearch...

Phylogenomic databases

HOGENOMHBG644467.
ProtClustDBPRK11655.

Enzyme and pathway databases

BioCycPLUM243265:PLU4378-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_PHOLL
AccessionPrimary (citable) accession number: Q7MZB5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 26, 2007
Last modified: January 25, 2012
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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