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Q7MXV0 (Q7MXV0_PORGI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase HAMAP MF_00570

Short name=NAPRTase HAMAP MF_00570
EC=2.4.2.11 HAMAP MF_00570
Gene names
Name:pncB HAMAP MF_00570 EMBL AAQ65307.1
Ordered Locus Names:PG_0057
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570 RuleBase RU003838 SAAS SAAS002638

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570 SAAS SAAS002638

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838

Subcellular location

Cytoplasm By similarity HAMAP MF_00570.

Sequence similarities

Belongs to the NAPRTase family. HAMAP MF_00570 RuleBase RU003838

Sequences

Sequence LengthMass (Da)Tools
Q7MXV0 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: B9919FB8A0A14784

FASTA39445,469
        10         20         30         40         50         60 
MGIIRSILDT DLYKFTTGYA YAKLFPRAYG EFRFIDRNRQ GFTEEFAELV RGEIRAMAAL 

        70         80         90        100        110        120 
SLTRDEKEFL QRELPYLPPI YIDFLDGFRF DPEEVTVSID AQGHLDIRAQ GLLYRVTLWE 

       130        140        150        160        170        180 
TPILAVISEL YYRFIGAEPD WKQVEEVTRS KGELMREHRA TFSIFGMRRR FSLEVEDRVT 

       190        200        210        220        230        240 
DILKQYAGES LFGTSNVHLA HKHGLRVSGT HPHEWIQFHG AIYGYKMANY VAMEDWINVY 

       250        260        270        280        290        300 
DGDLGTVLTD TYTTDVFMRN FSKKHAMLFT SLRHDSGDPE IFIEKAVRRY EELRVDPKIK 

       310        320        330        340        350        360 
YIIFSDSLTP QRAIEIQKLC AGRIKASFGI GTNLTNDVGG GVEPLNIVMK LWKCKMTAKD 

       370        380        390 
DWHYCVKLSD VDGKHTGEPE EILLAMNTLG IKPK 

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References

« Hide 'large scale' references
[1]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed: 12949112] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.
[2]"Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas gingivalis."
Fedorov A.A., Fedorov E.V., Sauder J.M., Burley S.K., Almo S.C.
Submitted (OCT-2006) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015924 Genomic DNA. Translation: AAQ65307.1.
RefSeqNP_904408.1. NC_002950.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2IM5X-ray2.20A/B/C/D1-394[»]
ProteinModelPortalQ7MXV0.
SMRQ7MXV0. Positions 3-391.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2552342.
GenomeReviewsGene locus PG_0057 in contig AE015924_GR.
KEGGpgi:PG0057.
NMPDRfig|242619.1.peg.49.
PATRIC22977266. VBIPorGin134034_0052.
TIGRPG_0057.

Phylogenomic databases

HOGENOMHBG325503.
OMASFGWGTN.
PhylomeDBQ7MXV0.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycPGIN242619:PG_0057-MONOMER.

Family and domain databases

HAMAPMF_00570. NAPRTase.
[Tree]
InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
KOK00763.
PANTHERPTHR11098:SF1. NAPRTase. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. Q_phspho_trans. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ7MXV0_PORGI
AccessionPrimary (citable) accession number: Q7MXV0
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)