Q7MX30 (RL1_PORGI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	PG_0391

Organism

Porphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]

Taxonomic identifier

242619 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000125708

Sequences

	Sequence		Length	Mass (Da)
	Q7MX30 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: F12554237FAA651A	FASTA	232	24,968
	10 20 30 40 50 60 MSKLTKKQKL AFSKIEPGKA YTISEASALV KEITTTNFDA SVDIDVRLGV DPRKANQMVR 70 80 90 100 110 120 GVVTLPHGTG KQIRVLALCS PDKEAEAKEA GADYVGLDEY IEKIKAGWTD IDVIITMPAI 130 140 150 160 170 180 MGKIGALGRV LGPRGLMPNP KSGTVTNDVG AAVKEVKAGK IDFKVDKTGI VHTSIGKVSF 190 200 210 220 230 SADQIRDNAR EFINTIIKLK PTTAKGTYIK SIYLSSTMSF GIKVDPKTVD EN

References

[1]

"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83." Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M. J. Bacteriol. 185:5591-5601(2003) [PubMed: 12949112] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015924 Genomic DNA. Translation: AAQ65596.1.
RefSeq	NP_904697.1. NC_002950.2.
3D structure databases
ProteinModelPortal	Q7MX30.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2551593.
GenomeReviews	Gene locus PG_0391 in contig AE015924_GR.
KEGG	pgi:PG0391.
NMPDR	fig|242619.1.peg.338.
PATRIC	22977894. VBIPorGin134034_0358.
TIGR	PG_0391.
Phylogenomic databases
HOGENOM	HBG297400.
OMA	FEDYIEK.
PhylomeDB	Q7MX30.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	PGIN242619:PG_0391-MONOMER.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_PORGI

Accession

Primary (citable) accession number: Q7MX30

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program