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Q7MVS5 (PSD_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:PG_0965
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029793
Chain189 – 22133Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029794

Sites

Site188 – 1892Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1891Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MVS5 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 4C0A10DC316F1642

FASTA22124,519
        10         20         30         40         50         60 
MKVHKESTGL LVSMATLFTG ICLSLFYFLG ASIVSYLVMI IAIFLYLLTI NFFRCPKRHS 

        70         80         90        100        110        120 
PFANDDRAVV APADGKIVAI EEVSENEILH ERCIQVSIFM SIFNVHANWF PCEGKVTHVS 

       130        140        150        160        170        180 
HKNGHFIAAY LPKSSTDNER SAIVIKTEKG ARILARQIAG ALARRIVTYA EVGDICSVDA 

       190        200        210        220 
HMGFIKFGSR VDVYLPLGSQ VEVKMDQKTV GNQTLIARLP E

« Hide

References

[1]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed: 12949112] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE015924 Genomic DNA. Translation: AAQ66094.1.
RefSeqNP_905195.1. NC_002950.2.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2552993.
GenomeReviewsGene locus PG_0965 in contig AE015924_GR.
KEGGpgi:PG0965.
NMPDRfig|242619.1.peg.836.
PATRIC22978994. VBIPorGin134034_0895.
TIGRPG_0965.

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
PhylomeDBQ7MVS5.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycPGIN242619:PG_0965-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_PORGI
AccessionPrimary (citable) accession number: Q7MVS5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: December 15, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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