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Q7MUV9 (G6PI_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:PG_1368
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180703

Sites

Active site2841Proton donor By similarity
Active site3051 By similarity
Active site4191 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MUV9 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 17052160EECFAFAF

FASTA44548,967
        10         20         30         40         50         60 
MERIRLDLSK TGSSVASYGE TAEKFNALLD NGTGRGSDFL GWVHLPSSIT EEELNAVEAA 

        70         80         90        100        110        120 
ATILRERCDY VINVGIGGSY LGARAVIEAL QNSFEAYRSD RENPVILYAG NNIGEDYLSE 

       130        140        150        160        170        180 
LLQFLRDKRF GIIYISKSGT TTEPAIAFRL LKGLLESQVG REDARERIVA VTDSAKGALR 

       190        200        210        220        230        240 
RMADEEGYRS FVIPDNVGGR FSVLTPVGLL PVAVAGFDIR QLVRGAADMQ AMTASDIPFS 

       250        260        270        280        290        300 
DNPALRYAAA RNALYAEGKK IEILANFHPK MHYIGEWWKQ LFGESEGKEE KGIFTATVDL 

       310        320        330        340        350        360 
TTDLHSMGQW MQEGERTIFE TVISVENQDT CLTIPSDSAD LDGLNFLAGK RVDEVNKMAE 

       370        380        390        400        410        420 
LGTRLAHVDG GVPNIRIILP QLDAYYIGQL FYFFEKAVGV SGYMLGVNPF DQPGVEGYKN 

       430        440 
NMFALLNKPG YETESAAMAG RLKEC 

« Hide

References

[1]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015924 Genomic DNA. Translation: AAQ66432.1.
RefSeqNP_905533.1. NC_002950.2.

3D structure databases

ProteinModelPortalQ7MUV9.
SMRQ7MUV9. Positions 4-442.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING242619.PG1368.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAQ66432; AAQ66432; PG_1368.
GeneID2551530.
KEGGpgi:PG1368.
PATRIC22979778. VBIPorGin134034_1273.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMAFGIINIS.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycPGIN242619:GHX8-1237-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PORGI
AccessionPrimary (citable) accession number: Q7MUV9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways