Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei34SubstrateUniRule annotation1
Binding sitei115SubstrateUniRule annotation1
Binding sitei171SubstrateUniRule annotation1
Binding sitei224ATPUniRule annotation1
Binding sitei315ATP; via carbonyl oxygenUniRule annotation1
Binding sitei346ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi375 – 378ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPGIN242619:G1G02-1567-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:PG_1677
OrganismiPorphyromonas gingivalis (strain ATCC BAA-308 / W83)
Taxonomic identifieri242619 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
Proteomesi
  • UP000000588 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001459841 – 418Phosphoglycerate kinaseAdd BLAST418

Proteomic databases

PRIDEiQ7MU77

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi242619.PG1677

Structurei

3D structure databases

ProteinModelPortaliQ7MU77
SMRiQ7MU77
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni18 – 20Substrate bindingUniRule annotation3
Regioni57 – 60Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
KOiK00927
OMAiDMIFDIG

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 2 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 2 hits
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

Q7MU77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIEQFNFAG KKAFVRVDFN VPLDDNFKIT DDTRIRAALP TLRKIIADGG
60 70 80 90 100
MTIIGSHLGR PKGVAPEFSL RHILPHVSEL LGVDVLFADD CIGADAMDKA
110 120 130 140 150
AKLKAGQVLL LENLRFYAEE EGKPRGLSDD ASDEEKAAAK KAVKAAQKEF
160 170 180 190 200
TQKLASMADC YVNDAFGTAH RAHASTALIA DYFDRDHKMF GYLMEKEVKA
210 220 230 240 250
VERVLHDIKR PFTAIMGGSK VSTKIEIIEN LLNKVDNLIL TGGMTYTFTK
260 270 280 290 300
AAGGRIGLSI VEDDKLDLAR DIVKKAAEKG VNLILSVDTK VADRFDNDAA
310 320 330 340 350
TQVCSNMEIP DDWMGMDIGP RSIEKFRKVI LESKTILWNG PTGVFEFDNF
360 370 380 390 400
SIGSKAVGEA IVEATANGAF SLVGGGDSVA CVNKFGLADK VSYVSTGGGA
410
LLEAIEGKTL PGIAAIQG
Length:418
Mass (Da):45,067
Last modified:December 15, 2003 - v1
Checksum:iADAC356F2A65B5F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015924 Genomic DNA Translation: AAQ66694.1
RefSeqiWP_005873486.1, NC_002950.2

Genome annotation databases

EnsemblBacteriaiAAQ66694; AAQ66694; PG_1677
KEGGipgi:PG_1677
PATRICifig|242619.8.peg.1554

Similar proteinsi

Entry informationi

Entry nameiPGK_PORGI
AccessioniPrimary (citable) accession number: Q7MU77
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 15, 2003
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health