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Q7MU77 (PGK_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:PG_1677
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 418418Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145984

Regions

Nucleotide binding375 – 3784ATP By similarity
Region18 – 203Substrate binding By similarity
Region57 – 604Substrate binding By similarity

Sites

Binding site341Substrate By similarity
Binding site1151Substrate By similarity
Binding site1711Substrate By similarity
Binding site2241ATP By similarity
Binding site3151ATP; via carbonyl oxygen By similarity
Binding site3461ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MU77 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: ADAC356F2A65B5F2

FASTA41845,067
        10         20         30         40         50         60 
MTIEQFNFAG KKAFVRVDFN VPLDDNFKIT DDTRIRAALP TLRKIIADGG MTIIGSHLGR 

        70         80         90        100        110        120 
PKGVAPEFSL RHILPHVSEL LGVDVLFADD CIGADAMDKA AKLKAGQVLL LENLRFYAEE 

       130        140        150        160        170        180 
EGKPRGLSDD ASDEEKAAAK KAVKAAQKEF TQKLASMADC YVNDAFGTAH RAHASTALIA 

       190        200        210        220        230        240 
DYFDRDHKMF GYLMEKEVKA VERVLHDIKR PFTAIMGGSK VSTKIEIIEN LLNKVDNLIL 

       250        260        270        280        290        300 
TGGMTYTFTK AAGGRIGLSI VEDDKLDLAR DIVKKAAEKG VNLILSVDTK VADRFDNDAA 

       310        320        330        340        350        360 
TQVCSNMEIP DDWMGMDIGP RSIEKFRKVI LESKTILWNG PTGVFEFDNF SIGSKAVGEA 

       370        380        390        400        410 
IVEATANGAF SLVGGGDSVA CVNKFGLADK VSYVSTGGGA LLEAIEGKTL PGIAAIQG 

« Hide

References

[1]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015924 Genomic DNA. Translation: AAQ66694.1.
RefSeqNP_905795.1. NC_002950.2.

3D structure databases

ProteinModelPortalQ7MU77.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING242619.PG1677.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAQ66694; AAQ66694; PG_1677.
GeneID2552606.
KEGGpgi:PG1677.
PATRIC22980356. VBIPorGin134034_1554.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
KOK00927.
OMAFGLADKM.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycPGIN242619:GHX8-1515-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_PORGI
AccessionPrimary (citable) accession number: Q7MU77
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways