Q7MTK2 (Q7MTK2_PORGI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malate dehydrogenase EMBL AAQ66930.1

Gene names

Name:	mdh EMBL AAQ66930.1
Ordered Locus Names:	PG_1949

Organism

Porphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]

Taxonomic identifier

242619 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the LDH/MDH superfamily. RuleBase RU003369

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle SAAS SAAS010945
Ligand	NAD SAAS SAAS010945
Molecular function	Oxidoreductase RuleBase RU003369
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro malate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase activity Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7MTK2 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 12C03CBF3E82970C	FASTA	334	36,187
	10 20 30 40 50 60 MSYLTEEKLT IVGAAGMIGS NMAQTAAMMR LTPNLCLYDP FAVGLEGVAE EIRHCGFEGL 70 80 90 100 110 120 NLTFTSDIKE ALTDAKYIVS SGGAPRKEGM TREDLLKGNA EIAAQLGKDI KSYCPDCKHV 130 140 150 160 170 180 IIIFNPADIT GLVTLIYSGL KPSQVTTLAG LDSTRLQSEL AKHFGIKQSL VTNTRTYGGH 190 200 210 220 230 240 GEQMAVFAST AKVNGTPLTD LIGTDKLTNE QWAELKQRVV KGGANIIKLR GRSSFQSPSY 250 260 270 280 290 300 VSIEMIRAAM GGEAFRWPAG CYVNVPGFEH IMMAMETTIT KDGVKYSDIN QLGNEAERAA 310 320 330 LKESYSHLAK LRDEVIAMGI IPAIADWKTV NPNL

References

[1]

"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83." Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M. J. Bacteriol. 185:5591-5601(2003) [PubMed: 12949112] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015924 Genomic DNA. Translation: AAQ66930.1.
RefSeq	NP_906031.1. NC_002950.2.
3D structure databases
HSSP	HSSP built from PDB template 1GV0 based on UniProtKB P80039.
ProteinModelPortal	Q7MTK2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2552158.
GenomeReviews	Gene locus PG_1949 in contig AE015924_GR.
KEGG	pgi:PG1949.
NMPDR	fig|242619.1.peg.1672.
PATRIC	22980866. VBIPorGin134034_1804.
TIGR	PG_1949.
Phylogenomic databases
HOGENOM	HBG347324.
OMA	DPNVAFK.
PhylomeDB	Q7MTK2.
ProtClustDB	CLSK823181.
Enzyme and pathway databases
BioCyc	PGIN242619:PG_1949-MONOMER.
Family and domain databases
InterPro	IPR001557. L-lactate/malate_DH. IPR022383. Lactate/malate_DH_C. IPR001236. Lactate/malate_DH_N. IPR015955. Lactate_DH/Glyco_Ohase_4_C. IPR010945. Malate_DH_type2. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.90.110.10. lact_mal_DH. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00024.
PANTHER	PTHR23382. MDH_SF1. 1 hit.
Pfam	PF02866. Ldh_1_C. 1 hit. PF00056. Ldh_1_N. 1 hit. [Graphical view]
PIRSF	PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAM	SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7MTK2_PORGI

Accession

Primary (citable) accession number: Q7MTK2

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)