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Protein

Guanylate kinase

Gene

gmk

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:VV0243
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002675 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001706391 – 207Guanylate kinaseAdd BLAST207

Structurei

3D structure databases

ProteinModelPortaliQ7MPW9
SMRiQ7MPW9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 184Guanylate kinase-likeUniRule annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7MPW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGTLYIVS APSGAGKSSL ISAMLEKNPT YAMKVSVSHT TRGMRPGEQD
60 70 80 90 100
GVHYHFVEKE HFEDLITKGE FLEYAEVFGN YYGTSRVWIE NTLDKGIDVF
110 120 130 140 150
LDIDWQGARQ IREQMPHAKS IFILPPSNGE LERRLNTRGQ DSEAVIAKRM
160 170 180 190 200
AEAKSEISHY NEYDYVIIND DFDTALMDFK AIIRAERLKQ DKQAAKYSGM

LDALLAE
Length:207
Mass (Da):23,449
Last modified:December 15, 2003 - v1
Checksum:i698C61BE484F00B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000037 Genomic DNA Translation: BAC93007.1
RefSeqiWP_011078918.1, NC_005139.1

Genome annotation databases

EnsemblBacteriaiBAC93007; BAC93007; BAC93007
GeneIDi33953612
KEGGivvy:VV0243

Similar proteinsi

Entry informationi

Entry nameiKGUA_VIBVY
AccessioniPrimary (citable) accession number: Q7MPW9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: December 15, 2003
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health